ⓘ Idazoxan

                                     

ⓘ Idazoxan

Idazoxan is a drug which is used in scientific research. It acts as both a selective α2 adrenergic receptor antagonist, and an antagonist for the imidazoline receptor. Idazoxan has been under investigation as an antidepressant, but it did not reach the market as such. More recently, it is under investigation as an adjunctive treatment in schizophrenia. Due to its alpha-2 receptor antagonism it is capable of enhancing therapeutic effects of antipsychotics, possibly by enhancing dopamine neurotransmission in the prefrontal cortex of the brain, a brain area thought to be involved in the pathogenesis of schizophrenia.

                                     
  • consumption that s produced by the alpha - 2 - adrenoceptor antagonist idazoxan Idazoxan may lead to the release of endogenous opioid peptides and increase
  • receptor antagonist and antagonist of the imidazoline receptor. Fluparoxan Idazoxan Chopin P, Colpaert FC, Marien M February 1999 Effects of alpha - 2 adrenoceptor
  • was never marketed. Allyl cyanide is starting material, and catechol. Idazoxan Piperoxan David J. Triggle 1997 Dictionary of pharmacological agents
  • M 1997 Presynaptic imidazoline receptors and non - adrenoceptor 3H - idazoxan binding sites in human cardiovascular tissues British Journal of Pharmacology
  • Christian Frelin 31 January 1989 Guanabenz, guanochlor, guanoxan and idazoxan bind with high affinity to non - adrenergic sites in pig kidney membranes
  • mass : 204.22 g mol, exact mass : 204.089878 may refer to: Ethotoin Fenozolone Idazoxan Nirvanol ORG - 26576 3 - Phenylazoacetylacetone Thozalinone Tryptophan
  • February 1984 Comparison of the alpha - adrenoceptor antagonist profiles of idazoxan RX 781094 yohimbine, rauwolscine and corynanthine Naunyn - Schmiedeberg s
  • an α2 - adrenergic receptor antagonist similarly to other imidazoles like idazoxan It was never marketed. Fenoxazoline has the precise same formula, albeit
  • withdrawing from adrenergic blockers. Examples include atipamezole, efaroxan, idazoxan yohimbine, and rauwolscine, Phentolamine. Lemke, KA June 2004 Perioperative