ⓘ MAP2K1IP1

                                     

ⓘ MAP2K1IP1

The protein encoded by this gene was identified as an interacting protein that binds specifically to MAP kinase MAP2K1/MEK1 and to MAP kinase MAPK2/ERK1. This protein enhances the activation of MAPK2, and thus is thought to function as an adaptor to enhance the efficiency of the MAP kinase cascade.

                                     
  • MAP 2 K 1 has been shown to interact with C - Raf, Phosphatidylethanolamine binding protein 1 MAP2K1IP1 GRB10, MAPK3, MAPK8 IP 3, MAPK 1 MP 1 and MAP 3 K 1 GRCh38:
  • PDZK 1 - interacting protein 1 is a protein that in humans is encoded by the PDZK 1 IP 1 gene. PDZK 1 IP 1 has been shown to interact with PDZK 1 GRCh38: Ensembl
  • CCNB 1 IP 1 cyclin B 1 interacting protein 1 Human CCNB 1 IP 1 genome location and CCNB 1 IP 1 gene details page in the UCSC Genome Browser. Maruyama K Sugano
  • protein 1 is an enzyme that in humans is encoded by the MAP 3 K 7 IP 1 gene. The protein encoded by this gene was identified as a regulator of the MAP kinase
  • MAPK8 JNK 1 and MAPK9 JNK 2 and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP 3 K 1 MEKK 1 MAP 3 K 2 MEKK 2 MAP 3 K 3 MEKK5
  • in MAP 3 K 7 IP 2 have been associated with human congenital heart defects. MAP 3 K 7 IP 2 has been shown to interact with: HDAC3, MAP 3 K 7 IP 1 MAP 3 K 7 IP 3, MAP 3 K 7
  • DUSP16, Mitogen - activated protein kinase 9, MAPK8, LRP 2 LRP 1 MAP 3 K 12, MAP 2 K 7, MAPK8 IP 2 and MAP 3 K 11. GRCh38: Ensembl release 89: ENSG00000121653 - Ensembl
  • well as in the organogenesis of liver. MAP 2 K 4 has been shown to interact with FLNC, MAPK8, MAPK8 IP 3 and AKT 1 GRCh38: Ensembl release 89: ENSG00000065559
  • ASK 1 has been shown to interact with: C - Raf, CDC25A, DAXX, DUSP19, EIF 2 AK 2 GADD45B, HSPA 1 A, MAP 2 K 6, MAP 3 K 7 and MAPK8 IP 3, PDCD6, PPP5C, RB 1 CC 1 TRAF 2 TRAF5
  • induced neuronal apoptosis. MAP 3 K 10 has been shown to interact with: CDC42, Huntingtin, KIF3A, MAPK8 IP 1 MAPK8 IP 2 and NEUROD 1 GRCh38: Ensembl release 89:
  • reported. MAP 3 K 7 has been shown to interact with: ASK 1 CHUK, MAP 2 K 6, MAP 3 K 7 IP 1 MAP 3 K 7 IP 2 MAP 3 K 7 IP 3, Mothers against decapentaplegic homolog 6, PPM 1 B, and
  • acid induced neuronal differentiation. MAP 3 K 12 has been shown to interact with MAPK8 IP 1 MAP 2 K 7 and MAPK8 IP 2 MAP 3 K 12, otherwise known as DLK, can initiate