ⓘ MSRA (gene)

                                     

ⓘ MSRA (gene)

Msr is ubiquitous and highly conserved. Human and animal studies have shown the highest levels of expression in kidney and liver. It carries out the enzymatic reduction of methionine sulfoxide MetO, the oxidized form of the amino acid methionine Met, back to methionine, using thioredoxin to catalyze the enzymatic reduction and repair of oxidized methionine residues. Its proposed function is thus the repair of oxidative damage to proteins to restore biological activity. Oxidation of methionine residues in tissue proteins can cause them to misfold or otherwise render them dysfunctional.

                                     
  • application in Microsoft Windows Michigan Shipwreck Research Associates Peptide - methionine S - S - oxide reductase, an enzyme MSRA gene a family of enzymes
  • humans is encoded by the MSRB2 gene The MRSB2 enzyme catalyzes the reduction of methionine sulfoxide to methionine. MSRA gene Methionine oxidation SEPX1
  • family, and it is expressed in a variety of adult and fetal tissues. MSRA gene MSRB2 Methionine oxidation GRCh38: Ensembl release 89: ENSG00000198736
  • Methionine Sulfoxide protein NADPH H Methionine protein NADP H2O MSRA gene MSRB2 enzyme SEPX1 enzyme Lee BC, Dikiy A, Kim HY, Gladyshev VN 2009