ⓘ AKAP3

                                     

ⓘ AKAP3

The A-kinase anchor proteins AKAPs are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A PKA and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family, and is expressed in testis only. The encoded protein contains an RII-binding domain, and is predicted to participate in protein-protein interactions with the R-subunit of the PKA. This protein is localized to the ribs of the fibrous sheath in the principal piece of the sperm tail. It may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.

                                     
  • FFAT motif in the N - terminal portion of AKAP11, similar to that found in AKAP3 GRCh38: Ensembl release 89: ENSG00000023516 - Ensembl, May 2017 GRCm38:
  • cancer and prostate cancer. AKAP 4 is over expressed in multiple myeloma MM AKAP 4 has been shown to interact with: AKAP3 and PRKAR1A. GRCh38: Ensembl
  • Some AKAPs are able to bind both regulatory subunits RI RII of PKA and are dual - specific AKAPs D - AKAP 1 and D - AKAP 2 AKAP 1 AKAP 2 AKAP3 AKAP 4 AKAP 5 AKAP6
  • encoded by the AKAP 9 gene. AKAP 9 is also known as Centrosome - and Golgi - localized protein kinase N - associated protein CG - NAP or AKAP 350 or AKAP 450 The A - kinase
  • 8 is an enzyme that, in humans, is encoded by the AKAP 8 gene. The A - kinase anchor proteins AKAPs are a group of structurally diverse proteins, which
  • mitochondrial is an enzyme that in humans is encoded by the AKAP 1 gene. The A - kinase anchor proteins AKAPs are a group of structurally diverse proteins that
  • protein 13 is an protein that in humans is encoded by the AKAP 13 gene. This protein is also called AKAP - Lbc because it encodes the lymphocyte blast crisis Lbc
  • anchor protein 12, aka AKAP 250, is an enzyme that in humans is encoded by the AKAP 12 gene. The A - kinase anchor proteins AKAPs are a group of structurally
  • protein 6 is an enzyme that in humans is encoded by the AKAP 6 gene. The A - kinase anchor proteins AKAPs are a group of structurally diverse proteins, which
  • A - kinase anchor protein 2 is an enzyme that in humans is encoded by the AKAP 2 gene. AKAP 2 has been shown to interact with PRKAR2A. Human PubMed Reference:
  • mitochondrial is an enzyme that in humans is encoded by the AKAP 10 gene. The A - kinase anchor proteins AKAPs are a group of structurally diverse proteins, which