ⓘ DLGAP2

                                     

ⓘ DLGAP2

The product of this gene is one of the membrane-associated guanylate kinases localized at postsynaptic density in neuronal cells. These kinases are a family of signaling molecules expressed at various submembrane domains and contain the PDZ, SH3 and the guanylate kinase domains. This protein may play a role in the molecular organization of synapses and in neuronal cell signaling. Alternatively spliced transcript variants encoding different isoforms have been identified, but their full-length nature is not known.

                                     
  • neurons. Dlgap 1 has five 14 - amino - acid repeats and three Pro - rich portions. DLGAP 1 has been shown to interact with: DLG1 DLG4 DYNLL1 DYNLL 2 SHANK 2 The interaction
  • SAP90 PSD - 95 - associated protein 4 SAPAP - 4 is a protein that in humans is encoded by the DLGAP 4 gene. DAP - 4 is a membrane - associated guanylate kinase found at the postsynaptic
  • up - regulated protein HURP is a protein that in humans is encoded by the DLGAP 5 gene. DLG7 is a kinetochore protein that stabilizes microtubules in vicinity
  • light chain 2 cytoplasmic is a protein that in humans is encoded by the DYNLL 2 gene. DYNLL 2 has been shown to interact with DLG4, C12orf40, DLGAP 1, MYO5A
  • CACNG 2 CASK DLG3 DLGAP 1 DLGAP2 DYNLL1 DYNLL 2 ERBB4 EXOC4 FYN FZD7 GRIK1 GRIK 2 GRIK5 GRIN 2 A GRIN 2 B GRIN 2 C HER 2 neu HGS KCNA 2 KCNA4 KCNA5 KCNJ12 Kir 2 1 LGI1
  • IP3R RYR and intracellular Ca 2 stores. SHANK 2 has been shown to interact with: ARHGEF7, Cortactin, DLG4, DLGAP 1, and DNM 2 GRCh38: Ensembl release 89:
  • CRIP 2 Cysteine - rich protein 2 DDX24: encoding enzyme ATP - dependent RNA helicase DDX24 DEGS 2 encoding protein Delta 4 - desaturase, sphingolipid 2 DLGAP 5:
  • Drosophila melanogaster in a pathway also known as the Scribble complex with DLGAP 5 Discs large and LLGL1 Lethal giant larvae as a tumor suppressor. In