ⓘ PTPRN2

                                     

ⓘ PTPRN2

Receptor-type tyrosine-protein phosphatase N2 also known as islet cell autoantigen-related protein and phogrin is an enzyme that in humans is encoded by the PTPRN2 gene. PTPRN and PTPRN2 are both found to be major autoantigens associated with insulin-dependent diabetes mellitus.

                                     
  • PTPRB, PTPRC, PTPRD, PTPRE, PTPRF, PTPRG, PTPRH, PTPRJ, PTPRK, PTPRM, PTPRN PTPRN2 PTPRO, PTPRQ, PTPRR, PTPRS, PTPRT, PTPRU, and PTPRZ. Ronald W. Dudek
  • is encoded by the PTPRN gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase PTP family and PTPRN subfamily. PTPs are
  • tumor growth. miR - 335 targets multiple pathways, including SOX4, MERTK, PTPRN2 and TNC, which contribute to metastasis - suppression. miR - 335 expression