ⓘ ZC3HC1

                                     

ⓘ ZC3HC1

Nuclear-interacting partner of ALK, also known as zinc finger C3HC-type protein 1, is a protein that in humans is encoded by the ZC3HC1 gene on chromosome 7. It is ubiquitously expressed in many tissues and cell types though exclusively expressed in the nuclear subcellular location. NIPA is a skp1 cullin F-box -type ubiquitin E3 ligase complex protein involved in regulating entry into mitosis. The ZC3HC1 gene also contains one of 27 SNPs associated with increased risk of coronary artery disease.

                                     
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  • Immune Response in Mice PLoS ONE. 3 10 e3548. doi: 10.1371 journal.pone.0003548. PMC 2569416. PMID 18958172. Hartman ZC Appledorn DM, Amalfitano A March
  • important for proper development of hematopoietic stem cells. MYST 3 MOZ MRD32 ZNF220 RUNXBP2 ZC 2 HC 6A GRCh38: Ensembl release 89: ENSG00000083168 - Ensembl, May
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  • Applied Pharmacology. 97 1 23 34. doi: 10.1016 0041 - 008X 89 90052 - 5. PMID 2563599. Goodspeed DC, Dunn TJ, Miller CD, Pitot HC March 1989 Human gamma - glutamyl
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  • Hudson LD December 1992 Novel member of the zinc finger superfamily: A C2 - HC finger that recognizes a glia - specific gene Molecular and Cellular Biology