ⓘ NLRC4

                                     

ⓘ NLRC4

The NLRC4 protein is highly conserved across mammalian species. It bears homology to the C. elegans Ced4 protein. It contains an n-terminal CARD domain, a central nucleotide binding/NACHT domain, and a c-terminal leucine rich repeat LRR domain. It belongs to a family of NLR proteins that includes the transcriptional co-activator CIITA and the canonical inflammasome protein NLRP3. A truncated murine NLRC4 was the first member of this family whose crystal structure was solved.

                                     
  • NLRC 5, short for NOD - like receptor family CARD domain containing 5, is an intracellular protein that plays a role in the immune system. NLRC 5 is a pattern
  • involved in sleep regulation. See NLRC4 for gene information NLRC4 also known as IPAF is the only known subset of the NLRC family to form an inflammasome
  • proteins containing this domain include: CIITA NAIP NLRC 3, NLRC4 NLRC 5 NLRP1, NLRP2, NLRP3, NLRP 4 NLRP5, NLRP6, NLRP7, NLRP8, NLRP9, NLRP10, NLRP11
  • BIRs NAIP NLRC C for CARD NOD1, NOD2, NLRC 3, NLRC4 NLRC 5 NLRP P for PYD NLRP1, NLRP2, NLRP3, NLRP 4 NLRP5, NLRP6, NLRP7, NLRP8, NLRP9, NLRP10
  • Commission Filipino: Pambansang Komisyon sa Ugnayang Paggawa, abbreviated NLRC is a quasi - judicial agency tasked to promote and maintain industrial peace
  • activators of NLRC4 inflammasome, and bacterial toxin nigericin that activates NLRP3 inflammasome. Caspase - 11 in mice and its human homolog caspase - 4 and - 5
  • than 20 subsets, including NOD1 and NOD2, NLRP3 also known as NALP3 NLRC4 All recognize bacterial, viral and toxic foreign products that are introduced
  • ASC and Nod - Like Receptor NLR Family CARD Domain - Containing Protein 4 NLRC4 through CARD - CARD interactions in the formation of inflammasomes. Caspase - 1
  • protease - activating factor, also known as NLR family, card domain containing 4 NLRC4 CARD, LRR, and NACHT - containing protein CLAN and Caspase recruitment
  • illegal dismissal case with the Regional Arbitration Branch No. VI of the NLRC which the Labor Arbiter found his dismissal illegal and ordered the team
  • apoptosis domain NAIP NLRC C for CARD domain NOD1 NOD2 NLRC 3 NLRC4 IPAF NLRC 5 NLRP P for Pyrin domain NLRP1 NLRP2 NLRP3 NLRP 4 NLRP5 NLRP6 NLRP7 NLRP8
  • PRRs that are known to induce inflammasome formation are NLRP3, NLRP1, NLRC4 AIM2 and Pyrin. These proteins contain oligomerization NACHT domains, CARD