ⓘ SEC13

                                     

ⓘ SEC13

Protein SEC13 homolog is a protein that in humans is encoded by the SEC13 gene.

The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It has similarities with yeast SEC13 and SEC31 proteins, which are required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins.

                                     
  • from endoplasmic reticulum ER This protein was found to colocalize with SEC13 one of the other components of COPII, in the subcellular structures corresponding
  • PMID 10788476. Stagg SM, Gurkan C, Fowler DM, et al. 2006 Structure of the Sec13 31 COPII coat cage Nature. 439 7073 234 8. doi: 10.1038 nature04339
  • proteins: Sar1, Sec 23, Sec 24, Sec13 and Sec 31. These proteins dimerize to form larger protein complexes: Sec 23p Sec 24p Heterodimer Sec 13 p Sec 31p Heterotetramer
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