ⓘ GOT1

                                     

ⓘ GOT1

Aspartate aminotransferase, cytoplasmic is an enzyme that in humans is encoded by the GOT1 gene.

Glutamic-oxaloacetic transaminase-phosphate pyridoxal dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. Is plays an important role in the metabolism of amino acids and the urea and tricarboxylic acid cycle. The two enzymes are homodimeric and show close homology.

                                     
  • mitochondrial forms, GOT1 and GOT 2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. Also, GOT 2 is a major participant
  • found in Caenorhabditis elegans, Plasmodium falciparum, and in mammals. GOT1 is normally associated closely with Sf2p encoded by sft2 which is another
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