ⓘ ORC3

                                     

ⓘ ORC3

The origin recognition complex ORC is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.

                                     
  • protein have been reported. ORC 4 has been shown to interact with: MCM2, MCM 3 MCM4, MCM6, ORC 1, ORC 2, ORC3 ORC 5, and ORC 6. GRCh38: Ensembl release 89:
  • origin of replication. ORC 2 has been shown to interact with: CDC6, DBF4, MCM10, MCM2 MCM4, MCM5, MCM6, MCM7, ORC 1, ORC3 ORC 4, ORC 5, ORC 6, and Replication
  • isoforms have been described. ORC 5 has been shown to interact with: MCM2, MCM 3 MCM4, MCM7, ORC 1, ORC 2, ORC3 and ORC 4. GRCh38: Ensembl release 89: ENSG00000164815
  • segregation with cytokinesis. ORC 6 has been shown to interact with MCM5, ORC 2, Replication protein A1, ORC 4, DBF4, ORC3 CDC45 - related protein, MCM4 and
  • An orc ɔːrk also spelled ork is a fictional humanoid creature akin to a goblin. Orcs were brought into modern usage by the fantasy writings of J.
  • The half - orc is a fictional creature born to mixed orc and human parentage in the Dungeons Dragons role - playing game. The half - orc is a playable race
  • orcs are a primitive race of savage, bestial, barbaric humanoid. The orc was one of the earliest creatures introduced in the D D game. The D D orc is
  • replication. The subunits of this complex are encoded by the ORC 1, ORC 2, ORC3 ORC 4, ORC 5 and ORC 6 genes. ORC is a central component for eukaryotic DNA replication
  • Orc is a proper name for one of the characters in the complex mythology of William Blake. A fallen figure, Orc is the embodiment of rebellion, and stands
  • subunit 1 is a protein that in humans is encoded by the ORC 1 gene. The origin recognition complex ORC is a highly conserved six subunits protein complex