ⓘ GSTO1

                                     

ⓘ GSTO1

Glutathione S-transferase omega-1 is an enzyme that in humans is encoded by the GSTO1 gene.

This gene encodes a member of the theta class glutathione-s-transferase-like protein family GSTTL. In Mouse, the encoded protein acts as a small stress response protein, likely involved in cellular redox homeostasis. This protein has dehydroascorbate reductase activity and may function in the glutathione-ascorbate cycle in the framework of the antioxidant metabolism.

                                     
  • 16 1 19 27. doi: 10.3892 ijmm.16. 1 19. PMID 15942673. Ozturk A, Desai PP, Minster RL, Dekosky ST, Kamboh MI 2005 Three SNPs in the GSTO1 GSTO 2 and
  • PMID 15855271. Ozturk A, Desai PP, Minster RL, et al. 2005 Three SNPs in the GSTO1 GSTO 2 and PRSS11 genes on chromosome 10 are not associated with age - at - onset
  • et al. published a paper revealing that glutathione S - transferase omega - 1 GSTO1 modifies the age - at - onset AAO of Alzheimer disease AD and PD. In May
  • C - terminal domain. EEF 1 E 1 EEF 1 G GDAP 1 GSTA 1 GSTA2 GSTA3 GSTA4 GSTA5 GSTM 1 GSTM2 GSTM3 GSTM4 GSTM5 GSTO1 GSTP 1 GSTT 1 GSTT2 GSTZ 1 MARS PGDS PTGDS2
  • stress, while glucagon decreases such gene expression. Omega - class GST GSTO genes, in particular, are associated with neurological diseases such as