ⓘ HGFAC

                                     

ⓘ HGFAC

Hepatocyte growth factor activator is a protein that in humans is encoded by the HGFAC gene.

The protein encoded by this gene belongs to peptidase family S1. It is first synthesized as inactive single-chain precursor before being activated to a heterodimeric form of endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to active form.

                                     
  • makes up the third strand of the EGF - module s major beta - sheet. F12 FN1 HGFAC PLAT Campbell ID, Baron M, Norman D, Willis A 1990 Structure of the
  • proteases belonging to MEROPS peptidase family S1A. ATF F12 F2 HABP2 HGF HGFAC KREMEN1 KREMEN2 LPA LPAL2 MST1 PIK3IP1 PLAT PLAU PLG PRSS12 ROR1
  • ELSPBP1 F12 FN1 HGFAC IGF2R LY75 MMP2 MMP9 MRC1 MRC1L1 MRC2 PLA2R1 SEL1L Fibronectin type I domain: F12 FN1 HGFAC PLAT Wah DA, Fernandez - Tornero
  • F10 F12 FAT FAT2 FAT4 FBN1 FBN2 FBN3 GAS6 HABP2 HBEGF HEG1 HGFAC HMCN1 HSPG2 ITGB5 JAG1 JAG2 LDLR LRP1 LRP10 LRP1B LRP2 LRP4