ⓘ TTRAP

                                     

ⓘ TTRAP

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor TNF receptor-75 and TNF receptor associated factors TRAFs, and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.

                                     
  • antioxidative pathways. TNFRSF1B has been shown to interact with: TRAF2, and TTRAP GRCh38: Ensembl release 89: ENSG00000028137 - Ensembl, May 2017 GRCm38:
  • INPP5E INPPL1 KIAA1706 OCRL PIB5PA SKIP SMPD2 SMPD3 SYNJ1 SYNJ2 TTRAP Nocturnin Mol CD, Kuo CF, Thayer MM, Cunningham RP, Tainer JA March 1995
  • protein has been shown to interact with TRAF2, TRAF3, TRAF6, TRAF5 and TTRAP CD40 molecule is a potential target for cancer immunotherapy. There are