ⓘ SYTL2

                                     

ⓘ SYTL2

The protein encoded by this gene is a synaptotagmin-like protein SLP that belongs to a C2 domain-containing protein family. The SLP homology domain SHD of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A RAB27A, which suggests a role in vesicle trafficking. Multiple alternatively spiced transcript variants encoding distinct isoforms have been observed.

                                     
  • encoded by the SYTL 1 gene. Model organisms have been used in the study of SYTL 1 function. A conditional knockout mouse line, called Sytl 1tm1a KOMP Wtsi
  • SYT17 SYT 2 SYT3 SYT4 SYT5 SYT6 SYT7 SYT8 SYT9 SYTL 1 SYTL2 SYTL 3 SYTL 4 SYTL 5 TOLLIP UNC13A UNC13B UNC13C UNC13D WWC 2 WWP1 WWP 2 PTEN Walker
  • Synaptotagmin - like protein 4 is a protein that in humans is encoded by the SYTL 4 gene. GRCh38: Ensembl release 89: ENSG00000102362 - Ensembl, May 2017 GRCm38:
  • factor. RAB27A has been shown to interact with: EXPH5, MYO5A, RPH3AL SYTL 1, and SYTL2 Rab27 GRCh38: Ensembl release 89: ENSG00000069974 - Ensembl, May 2017
  • retina and cerebellum. The encoded protein binds SYTL 4. STXBP1 has been shown to interact with STX 2 STX4 and STX1A. Overview of all the structural information
  • HGNC: 17167 Q9BQS 2 16118 SYT16 HGNC: 23142 Q17RD7 16119 SYT17 HGNC: 24119 Q9BSW7 16120 SYTL 1 HGNC: 15584 Q8IYJ3 16121 SYTL2 HGNC: 15585 Q9HCH5 16122 SYTL 3 HGNC: 15587