ⓘ DR1 (gene)

                                     

ⓘ DR1 (gene)

This gene encodes a TBP- TATA box-binding protein associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

                                     
  • HLA - DR1 DR1 is a HLA - DR serotype that recognizes the DRB 1 01 gene products. It has been observed to be common among centenarians. The serology for the
  • Dr1 - associated corepressor is a protein that in humans is encoded by the DRAP 1 gene Transcriptional repression is a general mechanism for regulating
  • biology, a gene is a sequence of nucleotides in DNA or RNA that encodes the synthesis of a gene product, either RNA or protein. During gene expression
  • same locus, DRB 1 The HLA - DRB 1 locus is ubiquitous and encodes a very large number of functionally variable gene products HLA - DR1 to HLA - DR 17 The HLA - DRB3
  • Gene nomenclature is the scientific naming of genes the units of heredity in living organisms. An international committee published recommendations for
  • A24 - Cw 0702: : DQ2 or A 1 B8 - DR1 - DQ5, none appear to be ancestral to A 1 DQ2. An A 1 DQ2 appears in India, however its major antigen genes superficially resemble
  • Horizontal gene transfer HGT or lateral gene transfer LGT is the movement of genetic material between unicellular and or multicellular organisms other
  • Homeobox protein DBX 1 also known as developing brain homeobox protein 1 is a protein that in humans is encoded by the DBX 1 gene The DBX 1 gene is a transcription
  • antigen, DRB 1 beta chain is a protein that in humans is encoded by the HLA - DRB 1 gene DRB 1 encodes the most prevalent beta subunit of HLA - DR Several alleles