ⓘ ADH4

                                     

ⓘ ADH4

Alcohol dehydrogenase 4 is an enzyme that in humans is encoded by the ADH4 gene.

This gene encodes class II alcohol dehydrogenase 4 Pi subunit, which is a member of a family of dehydrogenases of alcohol. The members of this family of enzyme metaboliziruet various substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and products of lipid peroxidation. Alcohol dehydrogenase class II is a homodimer consisting of 2 subunits of PI. It shows high activity in the oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized on chromosome 4 in a cluster of genes alcohol dehydrogenase.