ⓘ SYVN1

                                     

ⓘ SYVN1

This gene encodes a protein involved in endoplasmic reticulum ER-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3 UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms.

                                     
  • RNF180, RNF181, RNF182, RNF185, RNF207, RNF213, RNF215, RNFT 1 SH3MD4, SH3RF 1 SH3RF2, SYVN1 TIF 1 TMEM118, TOPORS, TRAF2, TRAF3, TRAF4, TRAF5, TRAF6, TRAF7
  • 16125 SYVN1 HGNC: 20738 Q86TM6 16126 SZRD 1 HGNC: 30232 Q7Z422 16127 SZT2 HGNC: 29040 Q5T011 16128 TAAR 1 HGNC: 17734 Q96RJ0 16129 TAAR2 HGNC: 4514 Q9P 1 P5 16130