ⓘ DNA repair and recombination protein RAD54-like

                                     

ⓘ DNA repair and recombination protein RAD54-like

DNA repair and recombination protein RAD54-like is a protein that in humans is encoded by the RAD54L gene.

The protein encoded by this gene belongs to the dead-as helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related Repair of double-strand breaks reparation of DNA breaks. The binding of this protein with DNA double-strand breaks, induces topological changes in DNA that facilitates the pairing of homologous DNA and stimulate DNA recombination.

                                     
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