ⓘ NAD(P)H dehydrogenase, quinone 2

                                     

ⓘ NAD(P)H dehydrogenase, quinone 2

NADH dehydrogenase, quinone 2, also known as QR2, is a protein that in humans is encoded by the NQO2 gene. It is a phase II detoxification enzyme which can carry out two or four electron reductions. Its mechanism of reduction is via a covalently bound zinc ion and a cocrystalized FAD. NQO2 contains two chains homologous in AA sequence but 7% different in structure. As a result, NQO2 contains two similar yet unique active sites. An important function of NQO2 is its activation on NRH. NQO2 can be inhibited by resveratrol.

                                     
  • oxidoreductase - 2 misleading QR 2 quinone reductase 2 N - ribosyldihydronicotinamide dehydrogenase quinone and NAD P H quinone oxidoreductase 2 misleading LIAO
  • Quinate dehydrogenase quinone EC 1.1.5.8, NAD P - independent quinate dehydrogenase quinate: pyrroloquinoline - quinone 5 - oxidoreductase is an enzyme
  • Alcohol dehydrogenase quinone EC 1.1.5.5, type III ADH, membrane associated quinohaemoprotein alcohol dehydrogenase is an enzyme with systematic name
  • be oxidised by a separate isoform of glycerol - 3 - phosphate dehydrogenase that uses quinone as an oxidant and FAD as a co - factor. As a result, there is
  • bacteria, some alcohol dehydrogenases catalyze the opposite reaction as part of fermentation to ensure a constant supply of NAD Genetic evidence from
  • this long - range conformational change event are the p H - coupled N 2 iron - sulfur cluster, the quinone reduction, and the transmembrane helix subunits of the
  • 1.6.5. 2 NAD P H dehydrogenase quinone EC 1.6.5.3: now EC 7.1.1. 2 EC 1.6.5.4: monodehydroascorbate reductase NADH EC 1.6.5.5: NADPH: quinone reductase
  • two dehydrogenases Using this shuttle system, NADH generated by cytosolic metabolisms including glycolysis is reoxidized to NAD reducing DHAP to G3 P and
  • qualified as malate dehydrogenase quinone In mutant strains of Escherichia coli lacking the activity of NAD - dependent malate dehydrogenase malate oxidase