ⓘ MMP16

                                     

ⓘ MMP16

Matrix metalloproteinase-16 is an enzyme that in humans is encoded by the MMP16 gene.

Proteins of the matrix metalloproteinase of MMP family, is involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction and tissue remodeling, as well as in disease such as arthritis and metastasis. Most MMP are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene produces at least two protocols, one of which encodes the membrane-bound form and another a soluble form of the protein. Both forms of activation of MMP2 protein in the cleavage. This gene was once referred to as MT-MMP2, but was renamed to T-ММР3 or MMP16.

                                     
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