ⓘ Centromere protein E

                                     

ⓘ Centromere protein E

Centromere-associated protein E is a protein that in humans is encoded by the CENPE gene.

Centromere-associated protein E is a kinesin-like motor protein that accumulates in G2 phase of the cell cycle. In contrast to other centromere-associated proteins is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed one of the motors responsible for the movement of chromosomes mammals and / or elongation of the spindle.

                                     
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