ⓘ UBE2D1

                                     

ⓘ UBE2D1

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport SFT, and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.

                                     
  • Ubiquitin - conjugating enzyme E 2 D 2 is a protein that in humans is encoded by the UBE 2 D 2 gene. The modification of proteins with ubiquitin is an important
  • UBE 2 E 1 UBE 2 E 2 UBE 2 E3 UBE 2 F putative UBE 2 G 1 UBE 2 G 2 UBE 2 H UBE 2 I UBE 2 J 1 UBE 2 J 2 UBE 2 K UBE 2 L3, UBE 2 L6 UBE 2 L 1 UBE 2 L 2 UBE 2 L4 are pseudogenes UBE 2 M
  • Ubiquitin - conjugating enzyme E 2 D 3 is a protein that in humans is encoded by the UBE 2 D 3 gene. The modification of proteins with ubiquitin is an important
  • Ubiquitin - conjugating enzyme E 2 G 1 is a protein that in humans is encoded by the UBE 2 G 1 gene. The modification of proteins with ubiquitin is an important
  • brain. UBE 3A has been shown to interact with: BLK, Lck, MCM7, MECP 2 Progesterone receptor, TSC 2 UBE2D1 UBE 2 D 2 UBE 2 L3, UBQLN 1 and UBQLN 2 GRCh38:
  • Ubiquitin - conjugating enzyme E 2 variant 2 is a protein that in humans is encoded by the UBE 2 V 2 gene. Ubiquitin - conjugating enzyme E 2 variant proteins constitute
  • Ubiquitin - conjugating enzyme E 2 variant 1 is a protein that in humans is encoded by the UBE 2 V 1 gene. Ubiquitin - conjugating E 2 enzyme variant proteins constitute
  • Ubiquitin - conjugating enzyme E 2 E 1 is a protein that in humans is encoded by the UBE 2 E 1 gene. The modification of proteins with ubiquitin is an important
  • Ubiquitin - conjugating enzyme E 2 L3 UBE 2 L3 also called UBCH7, is a protein that in humans is encoded by the UBE 2 L3 gene. As an E 2 enzyme, UBE 2 L3 participates in