ⓘ SF3B1

                                     

ⓘ SF3B1

This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex U2 snRNP. The splicing factor 3b/3a complex binds pre-mRNA upstream of the introns branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.

                                     
  • stretch in the C - terminus. SF3B2 has been shown to interact with SF 3 B 4, RBM7, SF3B1 and CDC5L. GRCh38: Ensembl release 89: ENSG00000087365 - Ensembl
  • transcription, splicing, and DNA repair. SF 3 B 3 has been shown to interact with SF3B1 Transcription initiation protein SPT 3 homolog and TAF9. GRCh38: Ensembl
  • transesterification step of splicing at the pre - mRNA branch site. SF 3 B 14 has been shown to interact with SF3B1 GRCh38: Ensembl release 89: ENSG00000115128 - Ensembl
  • factor 3 B subunit 4 is a protein that in humans is encoded by the SF 3 B 4 gene. This gene encodes one of four subunits of the splicing factor 3 B The protein
  • Splicing factor 3 B subunit 5 is a protein that in humans is encoded by the SF 3 B 5 gene. GRCh38: Ensembl release 89: ENSG00000169976 - Ensembl, May 2017
  • Splicing factor 3 subunit 1 is a protein that in humans is encoded by the SF 3 A 1 gene. This gene encodes subunit 1 of the splicing factor 3 a protein complex
  • Splicing factor 3 A subunit 3 is a protein that in humans is encoded by the SF 3 A 3 gene. This gene encodes subunit 3 of the splicing factor 3 a protein complex
  • The Super Famicom Naizou TV SF 1 スーパーファミコン内蔵テレビ SF 1 Supa Famikon Naizou Terebi SF 1 often described as the SF 1 SNES TV is a television set produced
  • SIAI - Marchetti SF 260 now Leonardo SF - 260 is an Italian light aircraft which has been commonly marketed as a military trainer and aerobatics aircraft. The SF 260
  • SF Airlines fleet consists of the following aircraft: SF Airlines Boeing 757 - 2Z0 SF SF Airlines Boeing 757 - 21 B SF SF Airlines Boeing 757 - 21 B SF Contact
  • Splicing factor 3 A subunit 2 is a protein that in humans is encoded by the SF 3 A2 gene. This gene encodes subunit 2 of the splicing factor 3 a protein complex