ⓘ WNT3A

                                     

ⓘ WNT3A

Protein Wnt-3a is a protein that in humans is encoded by the WNT3A gene.

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins were involved in carcinogenesis, adipogenesis, etc. and a number of other development processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of genetic family VNT. It encodes a protein shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene cluster with WNT14 gene, another family member, in chromosome 1q42 region.

                                     
  • of the WNT gene family. It encodes a protein showing 98 amino acid identity to mouse Wnt 3 protein, and 84 to human WNT3A protein, another WNT gene product
  • of mouse Wnt 14, and structural comparison between mouse Wnt 14 - Wnt3a gene cluster and human WNT 14 - WNT3A gene cluster Int. J. Mol. Med. 9 3 221 7.
  • development. This is apparent in systems such as the circulatory system where Wnt3a leads to proliferation and expansion of hematopoietic stem cells needed
  • Schmitz G, Sprong H March 2009 Mammalian Wnt3a is released on lipoprotein particles Traffic. 10 3 334 43. doi: 10.1111 j.1600 - 0854.2008.00872
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  • Census of vertebrate Wnt genes: isolation and developmental expression of Xenopus Wnt 2, Wnt 3 Wnt 9a, Wnt 9b, Wnt 10a, and Wnt 16 Developmental Dynamics
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  • Specifically, Wnt3a can directly induce MyoD expression via cis - element interactions with a distal enhancer and Wnt response element.. Wnt 1 from dorsal
  • site family, member 2, also known as WNT 2, is a human gene. This gene is a member of the WNT gene family. The WNT gene family consists of structurally
  • Protein Wnt - 7b is a protein that in humans is encoded by the WNT 7B gene. The WNT gene family consists of structurally related genes that encode secreted