ⓘ TAF10

                                     

ⓘ TAF10

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein TBP and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors GTFs to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs.

                                     
  • subunits of TFIID, TAF10 and TAF 11. There is a pseudogene located on chromosome 6. TAF 13 has been shown to interact with TAF 15, TAF 11, TAF10 and TATA binding
  • with several subunits of TFIID including TBP and the histone - fold protein TAF10 Alternatively spliced transcript variants have been described, but their
  • TAF interact with each other to form lobes in TFIID. Pairs known or suggested to exist in TFIID include TAF 6 - TAF 9, TAF 4 - TAF 12, TAF 11 - 13, TAF 8 - TAF10
  • 3 635 48. doi: 10 1016 j.cell.2006.09.026. PMID 17081983. Soutoglou E, Demeny MA, Scheer E, et al. 2005 The Nuclear Import of TAF10 Is Regulated by
  • shown to interact with: GCN5L2, Myc, SF3B3, SUPT7L, TADA3L, TAF 5, TAF 6L, TAF10 TAF 12, TAF 5L, TATA binding protein, Transcription initiation protein SPT3
  • community of the town of Pontypridd in the County Borough of Rhondda Cynon Taf located 10 miles north west of Cardiff, the capital city of Wales. Historically
  • TAF Linhas Aereas was an airline based in Fortaleza, Brazil. It operated regional passenger and cargo services. Today, the owner continues to do Services
  • TAFII55 TAF8 TAFII43 TAF 9 TAFII31 32 TAF 9B TAFII31L TAF10 TAFII30 TAF 11 TAFII28 TAF 12 TAFII20 15 TAF 13 TAFII18 TAF 15 TAFII68 Eukaryotic
  • Afon Taf High School Welsh: Ysgol Uwchradd Afon Taf is an 11 16 mixed secondary school in Troed - y - rhiw, Merthyr Tydfil, Merthyr Tydfil County Borough
  • initiation factor TFIID subunit 4 is a protein that in humans is encoded by the TAF 4 gene. Initiation of transcription by RNA polymerase II requires the activities
  • TBP - associated factor 250 kDa p250 is a protein that in humans is encoded by the TAF 1 gene. Initiation of transcription by RNA polymerase II requires the activities