ⓘ RFC4

                                     

ⓘ RFC4

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen PCNA and replication factor C RFC. RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.

                                     
  • distinct isoforms have been described. RFC 2 has been shown to interact with BRD 4 CHTF18, PCNA, RFC4 and RFC 5. GRCh38: Ensembl release 89: ENSG00000049541
  • distinct isoforms have been reported. RFC 5 has been shown to interact with: BRD 4 CHTF18, PCNA, RFC 2, and RFC4 GRCh38: Ensembl release 89: ENSG00000111445
  • distinct isoforms have been described. RFC 3 has been shown to interact with: BRD 4 CHTF18, PCNA, RFC 1, and RFC4 GRCh38: Ensembl release 89: ENSG00000133119
  • or RFC is a five - subunit protein complex that is required for DNA replication. The subunits of this heteropentamer are named Rfc 1, Rfc 2, Rfc 3, Rfc4 and
  • loader of prokaryotes. The eukaryotic equivalent to the DNA clamp loader is Replication Factor C, which is encoded by RFC 1, RFC 2, RFC 3, RFC4 and RFC 5.
  • protocol, IPv6. IPv 4 is described in IETF publication RFC 791 September 1981 replacing an earlier definition RFC 760, January 1980 IPv 4 uses a 32 - bit
  • Liege RFC Liege is a Belgian football club from the city of Liege. It currently plays in the Belgian First Amateur Division. Its matricule is 4 meaning
  • A Request for Comments RFC in the context of Internet governance, is a type of publication from the Internet Engineering Task Force IETF and the
  • founder clubs of the Welsh Rugby Union. In the early twentieth century Swansea RFC was an extremely successful club. For four consecutive seasons Swansea were