ⓘ TNNI1

                                     

ⓘ TNNI1

Troponin I, slow skeletal muscle is a protein that in humans is encoded by the TNNI1 gene. It is a tissue-specific subtype of troponin I, which in turn is a part of the troponin complex.

Gene TNNI1, troponin I type 1 skeletal muscle, slowly, also known as TNN1 and SSTNI, located in 1q31.3 in the genome of human chromosomes, encoding slow-twitch skeletal muscle of the ssTnI isoform of troponin I, the inhibitory subunit of the troponin complex in striated muscle myofilaments. Human TNNI1 covers 12.5 thousand nucleotides in genomic DNA and contains 9 exons and 8 its introns are. Of exon 2 to exon 8 contain coding sequences, encoding a protein of 21.7 KDA, consisting of 187 amino acids including the first methionine with the isoelectric point of intersection of 9.59.

                                     
  • isoform troponin I, TNNI1 1 q31.3, 191042 Fast - twitch skeletal muscle isoform troponin I, TNNI 2 11p15.5, 191043 Cardiac troponin I, TNNI 3 19q13.4, 191044
  • fast skeletal muscle is a protein that in humans is encoded by the TNNI 2 gene. The TNNI 2 gene is located at 11p15.5 in the human chromosomal genome, encoding
  • is encoded by the TNNI 3 gene. It is a tissue - specific subtype of troponin I, which in turn is a part of the troponin complex. The TNNI 3 gene encoding cardiac
  • TNNI 3 interacting kinase is a protein that in humans is encoded by the TNNI 3K gene. This gene encodes a protein that belongs to the MAP kinase kinase
  • their full length sequences have not been determined. PKD2L 1 has been shown to interact with TNNI 3. TRPP GRCh38: Ensembl release 89: ENSG00000107593 - Ensembl
  • syndrome critical region gene 1 - like 2 DSCR 1 L2 mRNA and by a novel DSCR 1 L2 mRNA isoform interact with cardiac troponin I TNNI 3 Gene. 372: 128 36. doi: 10
  • Polycystin 2 has been shown to interact with the proteins TRPC 1 PKD 1 and TNNI 3. HAX 1 TRPP GRCh38: Ensembl release 89: ENSG00000118762 - Ensembl, May
  • 2010 Coding sequence rare variants identified in MYBPC3, MYH6, TPM 1 TNNC 1 and TNNI 3 from 312 patients with familial or idiopathic dilated cardiomyopathy
  • PPP1R13B PPP 1 R13L PPP 1 R16A PPP 1 R16B PSMD10 RAI14 RFXANK RIPK4 RNASEL SHANK 1 SHANK2 SHANK3 SNCAIP TA - NFKBH TEX14 TNKS TNKS2 TNNI 3K TP53BP2
  • Heavy Chain 7 MYH7 Cardiac Troponin T 2 TNNT2 and Cardiac Troponin I TNNI 3 They also reviewed recent studies investigating genotype - phenotype associations