ⓘ Ephrin A1

                                     

ⓘ Ephrin A1

Ephrin A1 is a protein that in humans is encoded by the EFNA1 gene.

This gene encodes a member of the ephrin family of Eph. In the ephrins and Eph-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in the mediation of events in development, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-a class ARRA, which are attached to the membrane via glycosylphosphatidylinositol traction and ephrin-B EFNB class, which are transmembrane proteins. This gene encodes EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcripts encoding different isoforms identified through sequence analysis.

                                     
  • either the ephrin - A or ephrin - B ligands. Of the eight ephrins that have been identified in humans there are five known ephrin - A ligands ephrin - A1 - 5 that
  • Ephrin A5 is a protein that in humans is encoded by the EFNA5 gene. Ephrin A5 is a glycosylphosphatidylinositol GPI - anchored protein of the ephrin - A
  • Ephrin A4 is a protein that in humans is encoded by the EFNA4 gene. This gene encodes a member of the ephrin EPH family. The ephrins and EPH - related
  • Ephrin - A2 is a protein that in humans is encoded by the EFNA2 gene. This gene encodes a member of the ephrin family. The protein is composed of a signal
  • Ephrin A3 is a protein that in humans is encoded by the EFNA3 gene. This gene encodes a member of the ephrin EPH family. The ephrins and EPH - related
  • Ephrin - B 1 is a protein that in humans is encoded by the EFNB 1 gene. It is a member of the ephrin family. The encoded protein is a type I membrane protein
  • Ephrin - B2 is a protein that in humans is encoded by the EFNB2 gene. This gene encodes a member of the ephrin EPH family. The ephrins and EPH - related
  • Ephrin - B3 is a protein that in humans is encoded by the EFNB3 gene. EFNB3, a member of the ephrin gene family, is important in brain development as well
  • proteins Ephrins Ephs form the largest known subfamily of receptor tyrosine kinases RTKs Both Eph receptors and their corresponding ephrin ligands