ⓘ Peripherin 2

                                     

ⓘ Peripherin 2

Peripherin-2 is a protein, that in humans is encoded by the PRPH2 gene. Peripherin-2 is found in the rod and cone cells of the retina of the eye. Defects in this protein result in one form of retinitis pigmentosa, an incurable blindness.

Mutations in the gene PRPH2-related monitoring-related macular degeneration.

                                     
  • Peripherin is a type III intermediate filament protein expressed mainly in neurons of the peripheral nervous system. It is also found in neurons of the
  • peripheral nervous system can also contain the protein peripherin this is different from peripherin 2 that is expressed in the retina Thus mammalian neurofilaments
  • cGMP - gated channel and related glutamic acid - rich proteins interact with peripherin - 2 at the rim region of rod photoreceptor disc membranes J. Biol. Chem
  • cGMP - gated channel and related glutamic acid - rich proteins interact with peripherin - 2 at the rim region of rod photoreceptor disc membranes The Journal of
  • function which was detected by ERG. Also peripherin 2 was detected at the outer segment layer of the retina 2 weeks after injection and therapeutic effects
  • loss. The RDS gene provides instructions for making a protein called peripherin This protein is essential for the normal function of light - sensing photoreceptor
  • antibodies identify nuclear lamin B as a physiological attachment site for peripherin intermediate filaments Cell. 64 1 109 21. doi: 10.1016 0092 - 8674 91 90213 - I
  • 0.CO 2 - W. PMID 1000483. Knowles JA, Shugart Y, Banerjee P, et al. 1995 Identification of a locus, distinct from RDS - peripherin for autosomal
  • expressed in early development in the neuroblast along with α - internexin and peripherin As development continues into neurons the neurofilament triplet proteins
  • Plakophilin - 2 is a protein that in humans is encoded by the PKP 2 gene. Plakophilin 2 is expressed in skin and cardiac muscle, where it functions to link
  • Cofilin 2 muscle also known as CFL 2 is a protein which in humans is encoded by the CFL 2 gene. Cofilin is a widely distributed intracellular actin - modulating