ⓘ Beta defensin 1

                                     

ⓘ Beta defensin 1

Beta-defensin 1 is a protein that in humans is encoded by the DEFB1 gene.

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Family members defensin very similar to the sequence of the protein. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in the vicinity of defensin family member, alpha-1 and has been implicated in the pathogenesis of cystic fibrosis.

                                     
  • Beta defensins are a family of mammalian defensins The beta defensins are antimicrobial peptides implicated in the resistance of epithelial surfaces to
  • beta - defensin 1 is associated with increased risk of prostate cancer and clear - cell carcinomas. The first in vivo anti - cancer functions for defensin came
  • activity. Theta defensins form a single beta hairpin structure and therefore also represent a distinct group. Only alpha and beta defensins are expressed
  • Beta - defensin 2 BD - 2 also known as skin - antimicrobial peptide 1 SAP 1 is a peptide that in humans is encoded by the DEFB4 defensin beta 4 gene. Human
  • pattern of disulfide bonding, mammalian defensins are classified into alpha, beta and theta categories. Alpha - defensins which have been identified in humans
  • Beta - defensin 3 is a protein that in humans is encoded by the DEFB3 gene. HBD - 3 was first isolated from human lesional psoriatic scales. RT - PCR showed
  • Beta - defensin 103 is a protein that in humans is encoded by the DEFB103A gene. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils
  • θ - defensins are extremely divergent members of the defensin protein superfamily which includes alpha - beta - and big - defensins The θ - defensins appear
  • Beta - defensin 105 is a protein that is encoded by the DEFB105A gene in humans. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils
  • Beta - defensin 106 is a protein that in humans is encoded by the DEFB106A gene. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils
  • Beta - defensin 104 is a protein that in humans is encoded by the DEFB104A gene. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils
  • Zhao C, Wang I, Lehrer RI 24 Nov 1996 Widespread expression of beta - defensin hBD - 1 in human secretory glands and epithelial cells FEBS Lett. 396 2 3
  • Defensin alpha 5 DEFA5 also known as human alpha defensin 5 HD5 is a human protein that is encoded by the DEFA5 gene. DEFA5 is expressed in the Paneth