ⓘ Sjögren syndrome antigen B


ⓘ Sjogren syndrome antigen B

La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU OH elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogrens syndrome and systemic lupus erythematosus.