ⓘ TAF6

                                     

ⓘ TAF6

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein TBP and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors GTFs to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Four isoforms have been identified but complete transcripts have been determined for only three isoforms. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.

                                     
  • TAF6 - like RNA polymerase II p300 CBP - associated factor - associated factor 65 kDa subunit 6 L is an enzyme that in humans is encoded by the TAF 6 L gene. Initiation
  • TAF interact with each other to form lobes in TFIID. Pairs known or suggested to exist in TFIID include TAF6 - TAF 9, TAF 4 - TAF 12, TAF 11 - 13, TAF 8 - TAF 10
  • a nucleosome - like core in the TFIID complex. TAF 5 has been shown to interact with: TAF6 TAF 9, and TAF 15, TATA binding protein. GRCh38: Ensembl release
  • TAF 9 RNA polymerase II, TATA box binding protein TBP - associated factor, 32kDa, also known as TAF 9, is a protein that in humans is encoded by the TAF9
  • TBPL2 TAF 1 TAFII250 TAF 2 CIF150 TAF 3 TAFII140 TAF 4 TAFII130 135 TAF 4B TAFII105 TAF 5 TAFII100 TAF6 TAFII70 80 TAF 7 TAFII55 TAF 8 TAFII43
  • TBP - associated factor 250 kDa p250 is a protein that in humans is encoded by the TAF 1 gene. Initiation of transcription by RNA polymerase II requires the activities
  • 11 also known as TAFII28, is a protein that in humans is encoded by the TAF 11 gene. Initiation of transcription by RNA polymerase II requires the activities
  • Rhondda Cynon Taf County Borough Council Welsh: Cyngor Bwrdeistref Sirol Rhondda Cynon Taf is the governing body for Rhondda Cynon Taf one of the Principal
  • initiation factor TFIID subunit 4 is a protein that in humans is encoded by the TAF 4 gene. Initiation of transcription by RNA polymerase II requires the activities
  • presence of TAF 7. Thus, it is possible that TAF 7 is required for proper production of TAF 1 TAF 7 has been shown to interact with: TAF 15, TAF 1, and TATA