ⓘ Transferrin receptor 2

                                     

ⓘ Transferrin receptor 2

Transferrin receptor 2 is a protein that in humans is encoded by the TFR2 gene. This protein is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.

                                     
  • Transferrin receptor TfR is a carrier protein for transferrin It is needed for the import of iron into the cell and is regulated in response to intracellular
  • biological fluids of vertebrates.When a transferrin protein loaded with iron encounters a transferrin receptor on the surface of a cell, e.g., erythroid
  • Transferrin receptor protein 1 TfR1 also known as Cluster of Differentiation 71 CD71 is a protein that in humans is encoded by the TFRC gene. TfR1
  • type of Iron overload disorder associated with deficiencies in transferrin receptor 2 It exhibits an autosomal recessive inheritance pattern. RESERVED
  • and recycling of human beta 2 - adrenergic receptors between the plasma membrane and endosomes containing transferrin receptors The Journal of Biological
  • peptide initial part of the protein an extracellular transferrin receptor - binding region α1 and α 2 a portion that resembles immunoglobulin molecules
  • 2000 Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein
  • transferrin receptor mRNA. The transferrin receptor mRNA is rapidly degraded without the IRE - BP attached to it. The cell stops producing transferrin receptors
  • by the cell examples include LDL via the LDL receptor or iron via transferrin The role of receptor - mediated endocytosis is well recognized up take
  • MVBs Removal of recycling molecules such as transferrin receptors and mannose 6 - phosphate receptors continues during this period, probably via budding