ⓘ PSMB1

                                     

ⓘ PSMB1

Proteasome subunit beta type-1 also known as 20S proteasome subunit beta-6 is a protein that in humans is encoded by the PSMB1 gene. This protein is one of the 17 essential subunits that contributes to the complete assembly of 20S proteasome complex. In particular, proteasome subunit beta type-1, along with other beta subunits, assemble into two heptameric rings and subsequently a proteolytic chamber for substrate degradation. The eukaryotic proteasome recognized degradable proteins, including damaged proteins for protein quality control purpose or key regulatory protein components for dynamic biological processes. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.

                                     
  • humans is encoded by the PSMB 7 gene. This protein is one of the 17 essential subunits alpha subunits 1 - 7, constitutive beta subunits 1 - 7, and inducible subunits
  • humans is encoded by the PSMB 8 gene. This protein is one of the 17 essential subunits alpha subunits 1 7, constitutive beta subunits 1 7, and inducible subunits
  • subunit beta - 1 i is a protein that in humans is encoded by the PSMB 9 gene. This protein is one of the 17 essential subunits alpha subunits 1 - 7, constitutive
  • humans is encoded by the PSMB 4 gene. This protein is one of the 17 essential subunits alpha subunits 1 7, constitutive beta subunits 1 7, and inducible subunits
  • as 20S proteasome subunit beta - 1 based on systematic nomenclature is a protein that in humans is encoded by the PSMB 6 gene. This protein is one of the
  • humans is encoded by the PSMB 2 gene. This protein is one of the 17 essential subunits alpha subunits 1 7, constitutive beta subunits 1 7, and inducible subunits
  • humans is encoded by the PSMB 5 gene. This protein is one of the 17 essential subunits alpha subunits 1 7, constitutive beta subunits 1 7, and inducible subunits
  • PSMB 8 antisense RNA 1 head to head is a protein that in humans is encoded by the PSMB 8 - AS 1 gene. ENSG00000235540, ENSG00000234365, ENSG00000233089, ENSG00000233140
  • proteasome subunit beta - 3, is a protein that in humans is encoded by the PSMB 3 gene. This protein is one of the 17 essential subunits that contribute to
  • proteasome subunit beta - 2i is a protein that in humans is encoded by the PSMB 10 gene. This protein has a major role in the immune system as part of an
  • alpha type, 7 PSMA7 PSMB1 NM 002793 Homo sapiens proteasome prosome, macropain subunit, beta type, 1 PSMB1 mRNA PSMB 2 NM 002794 Homo sapiens
  • symptoms. The current known cause for the disorder is a mutation in the PSMB 8 gene or mutations in other closely related genes. The syndrome was first