ⓘ RAB5A

                                     

ⓘ RAB5A

RAB5A localizes to early endosomes where it is involved in the recruitment of RAB7A and the maturation of these compartments to late endosomes. It drives the maturation of endosomes by transporting vacuolar H+-ATPases V-ATPases from trans-Golgi network to endocytic vesicles.

                                     
  • Alvarez - Dominguez C, Stahl PD 1999 Interferon - gamma selectively induces Rab5a synthesis and processing in mononuclear cells J. Biol. Chem. 273 51
  • Chiariello M, Bruni CB, Bucci C Aug 1999 The small GTPases Rab5a Rab 5 b and Rab 5 c are differentially phosphorylated in vitro FEBS Lett. 453 1 2
  • Rab family of proteins is a member of the Ras superfamily of small G proteins. Approximately 70 types of Rabs have now been identified in humans. Rab
  • 1995 Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab 1A, Rab 3A, and Rab5A Proc. Natl
  • GTPase Rab 5 see RAB5A RAB 5 B, RAB 5 C a potent regulator of endocytic transport. It is mainly cytosolic, but a fraction co - localises with Rab 5 to early
  • 1994 Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab 1A, Rab 3A, and Rab5A Proceedings
  • Rab5a and rab 11a mediate agonist - induced trafficking of protease - activated receptor 2 American Journal of Physiology. Cell Physiology. 284 5 C1319 29
  • Rab Latin: Arba, Italian: Arbe, German: Arbey is an island in Croatia located just off the northern Croatian coast in the Adriatic Sea. The island is
  • Rab 11 family - interacting protein 5 is a protein that in humans is encoded by the RAB 11FIP 5 gene. RAB 11FIP 5 has been shown to interact with RAB 11A and RAB25
  • Ras - related protein Rab - 7a is a protein that in humans is encoded by the RAB 7A gene. Ras - related protein Rab - 7a is involved in endocytosis, which is a
  • Ras - related protein Rab - 4A is a protein that in humans is encoded by the RAB 4A gene. RAB 4A has been shown to interact with: CD2AP, KIF3B, RAB 11FIP1, RABEP1
  • Rab 27 is a member of the Rab subfamily of GTPases. Rab 27 is post translationally modified by the addition of two geranylgeranyl groups on the two C - terminal