ⓘ Dopamine receptor D1

                                     

ⓘ Dopamine receptor D1

Based upon Northern blot and in situ hybridization, DRD1 mRNA expression in the central nervous system is highest in the dorsal striatum caudate and putamen and ventral striatum nucleus accumbens and olfactory tubercle. Lower levels of DRD1 mRNA expression occur in the basolateral amygdala, cerebral cortex, septum, thalamus, and hypothalamus.

                                     
  • of receptors for dopamine was first proposed in 1976. There are at least five subtypes of dopamine receptors D1 D 2, D 3, D 4, and D 5. The D1 and D 5 receptors
  • The D1 D 2 dopamine receptor heteromer is a receptor heteromer consisting of D1 and D 2 protomers. D1 and D 2 receptors interact primarily through discrete
  • Dopamine receptor D 5, also known as D 1 BR, is a protein that in humans is encoded by the DRD5 gene. It belongs to the D1 - like receptor family along with
  • Dopamine receptor D 2, also known as D 2R, is a protein that, in humans, is encoded by the DRD2 gene. After work from Paul Greengard s lab had suggested
  • coupled to. The D1 - like class of dopamine receptors is coupled to Gαs olf and stimulates adenylate cyclase production, whereas the D 2 - like class is coupled
  • The D1 - like receptors are a subfamily of dopamine receptors that bind the endogenous neurotransmitter dopamine The D1 - like subfamily consists of two G
  • A dopamine receptor agonist DA is a compound that activates dopamine receptors There are two families of dopamine receptors D 2 - like and D1 - like, and
  • Dopamine receptor D 3 is a protein that in humans is encoded by the DRD3 gene. This gene encodes the D 3 subtype of the dopamine receptor The D 3 subtype
  • but not beta - adrenergic receptors The encoded protein interacts with dopamine receptor D1 and may interact with other DA receptor subtypes and or GPCRs