ⓘ Fibrinogen gamma chain

                                     

ⓘ Fibrinogen gamma chain

Fibrinogen gamma chain, also known as FGG, is a human gene found on Chromosome 4.

The protein encoded by this gene is the gamma component of fibrinogen, in the blood is a glycoprotein consisting of three pairs of nonidentical polypeptide chains. After vascular injury, fibrinogen is cleaved by thrombin to form fibrin, which is the most common component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing of the mRNA chain results in two transcript variants, a common thread and Im alternative spliced γ chain. Approximately 10% of the total plasma fibrinogen consists of I / γ fibrinogen with

                                     
  • the carboxy - terminus. Fibrinogen alpha chain has been shown to interact with tissue plasminogen activator. Fibrinogen gamma chain GRCh38: Ensembl release
  • the Bβ or β chain encoded by the FGB gene, and the fibrinogen gamma chain also termed the γ chain encoded by the FGG gene. All three genes are located
  • Fibrinogen beta chain also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation. The protein
  • Greenwich Group, an American investment firm Federation of Gay Games Fibrinogen gamma chain Foundation for God s nGlory, an American charity FGG a song by
  • visible fibrinogen band between the beta and gamma globulins. C - reactive protein is found in between the beta and gamma zones producing beta gamma fusion
  • occurring anticoagulant. Hementerin breaks the alpha FGA gamma FGG and beta FGB chains by degrading cross - linked fibrin. It has no degrading action
  • slow evolving gene, and fibrinogen gamma chain a fast evolving gene it is shown to evolve at a faster rate than fibrinogen GRCh38: Ensembl release
  • soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation - related reactions. After the description of fibrinogen and
  • MW 1996 Plasma factor XIII binds specifically to fibrinogen molecules containing gamma chains Biochemistry. 35 32 10448 53. doi: 10.1021 bi9606206
  • is similar to the β - and γ - chains of fibrinogen The carboxyl - terminus of the encoded protein consists of the fibrinogen - related domains FRED The