ⓘ Sepiapterin reductase

                                     

ⓘ Sepiapterin reductase

Sepiapterin reductase 7.8-dihydrobiopterin:NADP + oxidoreductase, EC 1.1.1.153 catalyzes the NADPH-dependent reduction of various carbonyl substances, including derivatives of pteridines, and belongs to a group of enzymes called aldo-keto reductases. SPR plays an important role in the biosynthesis of tetrahydrobiopterin.