ⓘ Ifenprodil

                                     

ⓘ Ifenprodil

Ifenprodil is an inhibitor of the NMDA receptor, specifically of GluN1 and GluN2B subunits. Additionally, ifenprodil inhibits GIRK channels, and interacts with alpha1 adrenergic, serotonin, and sigma receptors.

NMDA receptors are multimeric ionotropic glutamate receptors composed of four subunits. GluN1 is obligate for functional expression. Other units include GluN2A, GluN2B, and recently discovered GluN3 subunits. Ifenprodil selectively blocks NMDA receptors containing the GluN2B subunit.

                                     
  • Barbiturates Dextromethorphan Dextrorphan Dizocilpine Ethanol Ibogaine Ifenprodil Ketamine Kynurenic acid Memantine Nitrous oxide Perampanel Phencyclidine
  • The molecular formula C21H27NO2 molar mass: 325.44 g mol may refer to: Etafenone, a vasodilator Ifenprodil Norpropoxyphene SR 59230A
  • Butalamine C04AX24 Visnadine C04AX26 Cetiedil C04AX27 Cinepazide C04AX28 Ifenprodil C04AX30 Azapetine C04AX32 Fasudil ATC Anatomical Therapeutic Chemical
  • idrocilamide INN idronoxil USAN idropranolol INN idursulfase USAN ifenprodil INN ifetroban INN IFEX Bristol - Myers Squibb ifosfamide INN ifoxetine
  • given high densities in affected regions of the brain. Anti - ischemics ifenprodil and eliprodil, the binding of which increases blood flow, have also shown
  • Eliprodil ifenprodil site antagonist Esketamine dizocilpine site antagonist Hodgkinsine undefined site antagonist Ifenprodil ifenprodil site antagonist
  • Prendergast, MA Holley, RC Littleton, J 2002 Acamprosate, MK - 801, and ifenprodil inhibit neurotoxicity and calcium entry induced by ethanol withdrawal
  • antagonist - 550 nM NR1 NR2B subunit containing NMDA receptor antagonist ifenprodil site IC50 - 2, 000 nM The bioavailability of oral haloperidol ranges
  • Inhibition of G protein - activated inwardly rectifying K channels by ifenprodil Neuropsychopharmacology. 31 3 516 24. doi: 10.1038 sj.npp.1300844