ⓘ Antihistamine

                                     

ⓘ Antihistamine

Antihistamines are drugs which treat allergic rhinitis and other allergies. Typically people take antihistamines as an inexpensive, generic, over-the-counter drug that can provide relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects. Antihistamines are usually for short-term treatment. Chronic allergies increase the risk of health problems which antihistamines might not treat, including asthma, sinusitis, and lower respiratory tract infection. Consultation of a medical professional is recommended for those who intend to take antihistamines for longer-term use.

Although people usually use the word" the antihistamine” to describe drugs for allergies, doctors and scientists use this term to describe a class of drug that opposes the activity of the receptors of histamine in the body. In this sense, antihistamines subdivided in accordance with the histamine receptors that they act on. Two major classes of antihistamines are H 1-antihistamines and H 2-antihistamines.

H 1-antihistamines work by binding to histamine H 1 receptors in fat cells, smooth muscle and endothelium in the body, as well as in the tuberomammillary nucleus in the brain. Antihistamines, which target the histamine H 1-receptors are used to treat allergic reactions in the nose. In addition, they can be used to treat insomnia, motion sickness, or vertigo caused by problems with the inner ear. H2-antihistamines are associated with histamine H 2-receptors in the upper part of the gastrointestinal tract primarily in the stomach. Antihistamines, which target the histamine H2 receptor are used to treat gastric acid, for example, peptic ulcer disease and acid reflux.

Histamine receptors exhibit constitutive activity, so antihistamines can function as either a neutral antagonist or inverse agonist histamine receptors. Only a few currently on the market H 1-antihistamines are known to act as inverse agonists.

                                     
  • Among these are antidepressants, antipsychotics, anticonvulsants, and antihistamines as antiallergens, anti - motion sickness drugs, antipruritics, and hypnotics sedatives
  • Benadryl is a brand name for a number of different antihistamine medications used to stop allergies, including diphenhydramine, acrivastine and cetirizine
  • Piperoxan, also known as benodaine, is a drug which was the very first antihistamine to be discovered. This compound, derived from benzodioxan, was prepared
  • thiazinam is an antihistamine The USAN is thiazinamium chloride with a different counterion Since many of the uses of antihistamines involve conditions
  • Antazoline is a 1st generation antihistamine with anticholinergic properties used to relieve nasal congestion and in eye drops, usually in combination
  • Dexbrompheniramine is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically
  • antagonist antihistamine with anticholinergic properties drying and sedative side effects. Like all first generation antihistamines it is sedating
  • Novartis, is a drug that is used as an antipruritic and first - generation antihistamine It can be used in the treatment of asthma, hay fever, rhinitis and
  • Bamipine trade name Soventol is a pharmaceutical drug acting as an H1 antihistamine with anticholinergic properties. It is used as an antipruritic ointment
  • Oxomemazine guaifenesin is a sedative antihistamine plus expectorant. It is a combination of oxomemazine and guaifenesin. It is sold under a variety of
  • mephenhydramine is an antihistamine and anticholinergic. It was developed in Czechoslovakia and sold in hydrochloride form as an antihistamine Alfadryl It