ⓘ Insulin-degrading enzyme

                                     

ⓘ Insulin-degrading enzyme

Insulin-degrading enzyme, also known as IDE, is an enzyme.

Also known as insulysin or insulin protease, IDE is a large zinc-binding protease of the metalloprotease family, M16 known to cleave multiple short polypeptides that vary considerably in sequence. Other members of this family include mitochondrial processing peptidase, and protease dependence.

                                     
  • insulinase, insulin - degrading enzyme insulin protease, insulin proteinase, insulin - degrading neutral proteinase, insulin - specific protease, insulin - glucagon
  • the action of insulin - degrading enzyme An insulin molecule produced endogenously by the beta cells is estimated to be degraded within about one hour
  • PMID 3534791. Affholter JA, Fried VA, Roth RA December 1988 Human insulin - degrading enzyme shares structural and functional homologies with E. coli protease
  • be degraded by the cell. Degradation normally involves endocytosis of the insulin - receptor complex followed by the action of insulin degrading enzyme Most
  • matrix metalloproteinases, and M16 metalloproteinases such as Insulin Degrading Enzyme and Presequence Protease In the MEROPS database peptidase families
  • The insulin transduction pathway is a biochemical pathway by which insulin increases the uptake of glucose into fat and muscle cells and reduces the synthesis
  • IGFBP degrading enzymes referred to collectively as proteases. The IGF axis is also commonly referred to as the Growth Hormone IGF - 1 Axis. Insulin - like
  • Intact dilation and extraction, a form of abortion Insulin - degrading enzyme Insulysin, an enzyme Infectious disease epidemiology, the study of the patterns
  • Digestive enzymes are a group of enzymes that break down polymeric macromolecules into their smaller building blocks, in order to facilitate their absorption