ⓘ SREBP cleavage-activating protein

                                     

ⓘ SREBP cleavage-activating protein

Sterol regulatory element-binding protein cleavage-activating protein, also known as SREBP cleavage-activating protein or SCAP is a protein that in humans is encoded by the SCAP gene.

SCAP contains a Sterol-sensitive domain of the SSD and WD with the seven domains. Cholesterol-depleted cells, this protein binds to regulatory element binding proteins SREBPs Sterol and mediates their transport from the er to the Golgi apparatus. In SREBPs then a stabbing and to stimulate the biosynthesis of sterols.

                                     
  • transcriptionally active SREBP requires the cholesterol - sensing protein SREBP cleavage - activating protein SCAP which forms a complex with SREBP owing to interaction
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  • SCAP SREBP cleavage activating protein it makes the SCAP SREBP complex stay longer in the ER, thus prohibiting SCAP from carrying activated SREBP to the
  • 1 SREBF1 also known as sterol regulatory element - binding protein 1 SREBP - 1 is a protein that in humans is encoded by the SREBF1 gene. This gene is
  • HMGCR. SREBP cleavage - activating protein SCAP which regulates transcription of genes with sterol response elements by proteolytically activating sterol
  • reticulum proteins that block the processing of sterol regulatory element binding proteins SREBPs by binding to SREBP cleavage - activating protein SCAP
  • regulatory element - binding protein 2 SREBP - 2 also known as sterol regulatory element binding transcription factor 2 SREBF2 is a protein that in humans is encoded
  • liberates the N - terminal fragment of sterol regulatory element - binding protein SREBP transcription factors from membranes. S2P cleaves the transmembrane
  • Activating transcription factor 6, also known as ATF6, is a protein that, in humans, is encoded by the ATF6 gene and is involved in the unfolded protein