ⓘ CYP2E1

                                     

ⓘ CYP2E1

Cytochrome P450 2E1 is a member of the cytochrome P450 mixed-function oxidase system, which is involved in the metabolism of xenobiotics in the body. This class of enzymes is divided up into a number of subcategories, including CYP1, CYP2, and CYP3, which as a group are largely responsible for the breakdown of foreign compounds in mammals.

In CYP2 subfamily is responsible for the majority of P450-mediated metabolism of the drug in the human body. And CYP2E1 itself is a relatively small number of these reactions ~4% of the known P450-mediated oxidation of drugs, and related enzymes CYP1A2 and CYP3A4 are responsible for the breakdown of many toxic chemicals and environmental carcinogens that enter the body, in addition to basic metabolic reactions such as fatty acid oxidation.