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RNASET2

Ribonuclease T2 is an enzyme that in humans is encoded by the RNASET2 gene. This ribonuclease gene is a novel member of the RH / T2 / s-glycoprotein class of extracellular ribonucleases. This is one copy of the gene that corresponds to 6q27, a re ...

RNF8

E3 ubiquitin-protein ligase RNF8 is an enzyme that in humans is encoded by the RNF8 gene. RNF8 has activity both in immune system functions and in DNA repair.

RNF39

RING finger protein 39 is a protein that in humans is encoded by the RNF39 gene. This gene lies within the major histocompatibility complex class I region on chromosome 6. Studies of a similar rat protein suggest that this gene encodes a protein ...

RPS6KA2

Ribosomal protein S6 kinase alpha-2 is an enzyme that in humans is encoded by the RPS6KA2 gene. This gene encodes a member of the RSK family of ribosomal S6 kinases and serine threonine kinases. This kinase contains 2 nonidentical kinase catalyti ...

RSPH3

Radial spoke head protein 3 homolog, also known as radial spoke head-like protein 2, is a protein that in humans is encoded by the RSPH3 gene.

RSPH4A

TRadial spoke head protein 4 homolog A appears to be a component the radial spoke head, as determined by homology to similar proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. Radial spokes, which are regularly spaced ...

SEC63

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum ER membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is spec ...

SENP6

Ubiquitin-like molecules UBLs, such as SUMO1, are structurally related to ubiquitin and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified protei ...

SERAC1

Serine active site-containing protein 1, or Protein SERAC1 is a protein in humans that is encoded by the SERAC1 gene. The protein encoded by this gene is a phosphatidylglycerol remodeling protein found at the interface of mitochondria and endopla ...

SESN1

Sestrin 1, also known as p53-regulated protein PA26, is a protein that in humans is encoded by the SESN1 gene. This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellu ...

SHPRH

SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases.

Sirtuin 5

Sirtuin 5, also known as SIRT5 is a protein which in humans in encoded by the SIRT5 gene and in other species by the orthologous Sirt5 gene. This gene encodes a member of the family sirtuin proteins, homologs to the yeast Sir2 protein. Family mem ...

SKIV2L

Helicase SKI2W is an enzyme that in humans is encoded by the SKIV2L gene. This enzyme is a human homologue of yeast SKI2, which may be involved in antiviral activity by blocking translation of poly deficient mRNAs. The SKIV2L gene is located in t ...

SLC22A1

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three ...

SLC26A8

This gene is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic number and size of exons and protein aa length among species structures yet have markedly different tissue expression patte ...

SMAP1

Stromal membrane-associated protein 1 is a protein that in humans is encoded by the SMAP1 gene. The protein encoded by this gene similar to the membrane-associated stromal mouse protein-1. This similarity suggests that this gene product is a pers ...

SMOC2

This gene has been shown mutated in clinical cases of major dental developmental defects. Brachicephalicus dogs show a shortening of the muzzle, together with the extension of the hard palate. This skull shape is strongly associated with disorder ...

SNX3

Sorting nexin-3 is a protein that in humans is encoded by the SNX3 gene. This gene encodes a member is below a sort of family. Members of this family contain a phox px domain, which is the area of the binding of phosphatidylinositol and are invol ...

SNX9

Sorting nexin-9 is a protein that in humans is encoded by the SNX9 gene. This gene encodes a member is below a sort of family. Members of this family contain a phox px domain, which is the area of the binding of phosphatidylinositol and are invol ...

Sobp

Sine oculis-binding protein homolog also known as Jackson circler protein 1 is a protein that in humans is encoded by the SOBP gene. The first SOBP gene was identified in Drosophila melanogaster in a yeast two-hybrid screen that used the SIX doma ...

SPATS1

Spermatogenesis associated serine rich 1 is a protein which in humans is encoded by the SPATS1 gene. It is also known by the aliases Dishevelled-DEP domain interacting protein, Spermatogenesis Associated 8, and serin-rich spermatogenic protein 1. ...

SPDEF

SAM pointed domain-containing Ets transcription factor is a protein that in humans is encoded by the SPDEF gene. PDEF is an ETS transcription factor expressed in the epithelial cells of the prostate. It acts as an androgen-independent transactiva ...

SRPK1

This gene encodes a serine/arginine protein kinase specific for the SR serine/arginine-rich domain family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive ...

SSR1

Translocon-associated protein subunit alpha is a protein that in humans is encoded by the SSR1 gene. Signal sequence receptor SSR glikozilirovanie endoplasmic reticulum er membrane receptor associated with protein translocation across the er memb ...

STK19

Serine/threonine-protein kinase 19 is an enzyme that in humans is encoded by the STK19 gene. This gene encodes a serine / threonine kinase is localized predominantly in the nucleus. Its specific function is unknown, it is possible that phosphoryl ...

SUMO4

This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins subcellular localization, stability, or activity. The protein described in ...

Synaptojanin

Synaptojanin is a protein involved in vesicle uncoating in neurons. This is an important regulatory lipid phosphatase. It dephosphorylates the D-5 position phosphate from phosphatidylinositol -trisphosphate and Phosphatidylinositol -bisphosphate. ...

SYNCRIP

Synaptotagmin binding, cytoplasmic RNA interacting protein, also known as Heterogeneous nuclear ribonucleoprotein Q is a protein that in humans is encoded by the SYNCRIP gene.

SYNGAP1

Synaptic Ras GTPase-activating protein 1, also known as synaptic Ras-GAP 1 or SYNGAP1, is a protein that in humans is encoded by the SYNGAP1 gene. SYNGAP1 is a ras GTPase-activating protein that is critical for the development of cognition and pr ...

T-cell activation RhoGTPase activating protein

This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases, including rheumatoid arthritis, cel ...

T-complex 1

This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex CCT, also known as the TCP1 ring complex TRiC. This complex consists of two identical stacked rings, each containing eight different proteins. Unfo ...

TAF8

Transcription initiation factor TFIID subunit 8 is a protein that in humans is encoded by the TAF8 gene. This gene encodes one of several Tata-binding protein TBP-associated factors TAFs, which are integral parts of a common transcription factor ...

TAF11

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID TFIID, which binds to the core promoter to position the polymerase pr ...

Tapasin

This gene encodes a transmembrane glycoprotein that mediates interaction between newly assembled major histocompatibility complex MHC class I molecules and the transporter associated with antigen processing TAP, which is required for the transpor ...

TCP11

Model organisms have been used in the study of TCP11 function. A conditional knockout mouse line called Tcp11 tm1aEUCOMMWtsi was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen ...

Tenascin X

A member of the tenascin family, tenascin X also known as hexabrachion-like protein is a glycoprotein that is expressed in connective tissues including skin, joints and muscles. In humans, tenascin X is encoded by the TNXB gene.

TFB1M

Dimethyladenosine transferase 1, mitochondrial, Transcription factor B1, mitochondrial is a mitochondrial enzyme that in 12-Eiael mag ingay is encoded by the TFB1M gene. TFB1M is a mitochondrial methyltransferase, which uses S-adenosyl methionine ...

TFEB

TFEB is a master gene for lysosomal biogenesis. It encodes a transcription factor that coordinates expression of lysosomal hydrolases, membrane proteins and genes involved in autophagy. Upon nutrient depletion and under aberrant lysosomal storage ...

Thiopurine methyltransferase

Thiopurine methyltransferase or thiopurine S-methyltransferase is an enzyme that in humans is encoded by the TPMT gene. A pseudogene for this locus is located on chromosome 18q.

Thrombospondin-2

Thrombospondin-2 is a protein that in humans is encoded by the THBS2 gene. The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that causes cell-to-cell and cell-matrix interact ...

TINAG

Tubulointerstitial nephritis antigen is a protein that in humans is encoded by the TINAG gene. TINAG basement membrane glycoprotein initially identified as a target of antibodies in some forms of immunologically mediated tubulointerstitial nephritis.

TLX

Nuclear receptor TLX also known as NR2E1 is a protein that in humans is encoded by the NR2E1 gene. TLX is a member of the nuclear receptor family of intracellular transcription factors.

TMEM242

Transmembrane protein 242 is a protein that in humans is encoded by the TMEM242 gene. The tmem242 gene is located on chromosome 6, on the long arm, in band 2 section 5.3. This protein is also commonly called C6orf35, BM033, and UPF0463 Transmembr ...

TNFAIP3

Tumor necrosis factor, alpha-induced protein 3 or A20 is a protein that in humans is encoded by the TNFAIP3 gene. This gene was identified as the gene expression which is rapidly induced by the tumor necrosis factor TNF. The protein encoded by th ...

TPD52L1

This gene encodes a member of the tumor protein D52 TPD52 family. The encoded protein contains a coiled-coil domain and may form homo- or hetero-dimer with TPD52 family members. The protein is reported to be involved in cell proliferation and cal ...

TRAF3IP2

Adapter protein CIKS is a protein that in humans is encoded by the TRAF3IP2 gene. This gene encodes a protein involved in regulating responses to cytokines by members of the Rel / in NF-kappaB transcription factor family. These factors play an im ...

TRAM2

Translocating chain-associated membrane protein 2 is a protein that in humans is encoded by the TRAM2 gene. TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of secretory and mem ...

Transcription initiation protein SPT3 homolog

Transcription initiation protein SPT3 homolog has been shown to interact with GCN5L2, TAF6L, TADA3L, TAF5L, SF3B3, SUPT7L, Myc, TAF9, Transformation/transcription domain-associated protein, TAF12, TAF10, TAF4 and DDB1.

Transmembrane protein 242

Transmembrane Protein 242 is a protein encoded by the Transmembrane 242 gene located in the human genome. The tmem242 gene is located on chromosome 6, on the long arm, in band 2 section 5.3. This protein is also commonly called C6orf35, BM033, an ...

TREM1

Monocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors e.g., FPR1, Fc receptors see MIM 146790, CD14 and Toll-like receptors e.g., ...