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Chromosome 1 open reading frame 112

Chromosome 1 open reading frame 112, is a protein that in humans is encoded by the C1orf112 gene, and is located at position 1q24.2. C1orf112 encodes for seventeen variants of mRNA, fifteen of which are functional proteins. C1orf112 has a determi ...

Chromosome 1 open reading frame 162

Chromosome 1 open reading frame 162 is a protein that in humans is encoded by the C1orf162 gene. It has been found to be hypomethylated in instances of gastric cancer.

Chromosome 1 open reading frame 194

Chromosome 1 open reading frame 194 is a gene from Homo sapiens. The function of the protein coded by the gene is still not understood by the scientific community.

Chymosin

Chymosin or rennin is a protease found in rennet. It is an aspartic endopeptidase belonging to MEROPS A1 family. It is produced by newborn ruminant animals in the lining of the abomasum to curdle the milk they ingest, allowing a longer residence ...

Chymotrypsin-C

Chymotrypsin C is a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity.

Cingulin

Cingulin is a cytosolic protein encoded by the CGN gene in humans localized at tight junctions of vertebrate epithelial and endothelial cells.

CKS1B

The CKS1B protein binds to the catalytic subunit of the cyclin-dependent kinases and is essential for their biological function. The CKS1B mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a ...

CLDN19

Claudin-19 is a protein that in humans is encoded by the CLDN19 gene. It belongs to the group of claudins. Claudin-19 has been implicated in magnesium transport. Claudins, such as CLDN19, are transmembrane proteins in tight junctions. Tight junct ...

CLK2

This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have shown to interact with, and phosphorylate, serine/arginine-rich SR proteins of the spliceosomal complex, which is a part of the regulatory m ...

CLSPN

Xenopus claspin is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in the presence of DNA templates in Xenopus egg extracts. The human gene appears to be the homolog Xenopus claspin and it ...

CMPK

Uridine monophosphate UMP/cytidine monophosphate CMP kinase EC 2.7.4.4 catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP dCMP, resulting in the formation of ADP and the corresponding nucleoside diphosphate. These nucleoside di ...

CNKSR1

This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway.

COA6

Cytochrome c oxidase assembly factor 6 is a protein that in humans is encoded by the COA6 gene. Mitochondrial respiratory chain Complex IV, or cytochrome c oxidase, is the component of the respiratory chain that catalyzes the transfer of electron ...

COG2

Conserved oligomeric Golgi complex subunit 2 is a protein that in humans is encoded by the COG2 gene. Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modificat ...

Collagen, type IX, alpha 2

Collagen alpha-2 chain is a protein that in humans is encoded by the COL9A2 gene. This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, ...

Collagen, type VIII, alpha 2

Collagen alpha-2 chain is a protein that in humans is encoded by the COL8A2 gene. Mutations of the gene are linked to posterior polymorphous dystrophy type 2.

Collagen, type XI, alpha 1

The COL11A1 gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Three transcript variants ...

Collagen, type XVI, alpha 1

This gene encodes the alpha chain of type XVI collagen, a member of the FACIT collagen family fibril-associated collagens with interrupted helices. Members of this collagen family are found in association with fibril-forming collagens such as typ ...

Complement component 1q

The complement component 1q is a protein complex involved in the complement system, which is part of the innate immune system. C1q together with C1r and C1s form the C1 complex. Antibodies of the adaptive immune system can link the antigen to for ...

Complement receptor 2

Complement receptor type 2, also known as complement C3d receptor, Epstein-Barr virus receptor, and CD21, is a protein that in humans is encoded by the CR2 gene. CR2 is involved in the complement system. It binds to the inactive iC3b derived from ...

Contactin 2

The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol GPI-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon co ...

COPA (gene)

In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins COPs. Seven coat proteins have been identified, and they represent subunits of a co ...

CRB1

Crumbs homolog 1 is a protein that in humans is encoded by the CRB1 gene. This gene encodes a protein that is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila, crumbs is locali ...

CREG1

Protein CREG1 is a protein that in humans is encoded by the CREG1 gene. For the adenovirus E1A protein as it activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene, ...

CRYZ

Quinone oxidoreductase is an enzyme that in humans is encoded by the CRYZ gene. Crystallins are divided into two classes: taxon-specific, or enzyme, and ubiquitous. The last class represents the main protein of eye lens of vertebrates and maintai ...

CSRP1

Cysteine and glycine-rich protein 1 is a protein that in humans is encoded by the CSRP1 gene. CSRP1 is a member of the family TSSRP genes encoding a group of lim domain proteins which may be involved in regulatory processes important for developm ...

CTNNBIP1

The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF T-cell transcription factor family members. The encoded protein is a negative regulator of the Wnt signaling pathway.

CTP synthase 1

The catalytic conversion of uridine triphosphate UTP to cytidine triphosphate CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. This enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a ...

CYP2J2

Cytochrome P450 2J2 is a protein that in humans is encoded by the CYP2J2 gene. CYP2J2 is a member of the cytochrome P450 superfamily of enzymes. The enzymes are oxygenases which catalyze many reactions involved in the metabolism of drugs and othe ...

CYP4A11

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This prot ...

CYP4A22

CYP4A22 also known as fatty acid omega-hydroxylase is a protein which in humans is encoded by the CYP4A22 gene. This gene encodes a member of cytochrome P450 superfamily of enzymes. Cytochrome P450 proteins are monooxygenases which catalyze many ...

CYP4B1

Cytochrome P450 4B1 is a protein that in humans is encoded by the CYP4B1 gene. This gene encodes a member of cytochrome P450 superfamily of enzymes. Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabo ...

CYP4X1

CYP4X1 is a protein which in humans is encoded by the CYP4X1 gene. This gene encodes a member of cytochrome P450 superfamily of enzymes. Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and syn ...

CYP4Z1

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene ...

Cystathionine gamma-lyase

Cystathionine gamma-lyase is an enzyme which breaks down cystathionine into cysteine, α-ketobutyrate, and ammonia. Pyridoxal phosphate is a prosthetic group of this enzyme. Gamma-Lyase Cystathionine also catalyzes the following reactions of elimi ...

Cytidine deaminase

Cytidine deaminase is an enzyme that in humans is encoded by the CDA gene. This gene encodes an enzyme involved in pyrimidine salvation. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine a ...

DAP3

28S ribosomal protein S29, mitochondrial, also known as death-associated protein 3, is a protein that in humans is encoded by the DAP3 gene on chromosome 1. This gene encodes a 28S subunit protein of the mitochondrial ribosome and plays key roles ...

DCAF8

This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene.

DCLRE1B

DNA cross-link repair 1B protein is a protein that in humans is encoded by the DCLRE1B gene. These DNA cross-links prevent strand separation, thus physically blocking transcription, replication and segregation of DNA. DCLRE1B is one of several ev ...

DDOST

Dolichyl-diphosphooligosaccharide - protein glycosyltransferase 48 kDa subunit is an enzyme that in humans is encoded by the DDOST gene. This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high m ...

DDX20

Probable ATP-dependent RNA helicase DDX20, also known as DEAD-box helicase 20 and gem-associated protein 3, is an enzyme that in humans is encoded by the DDX20 gene.

Death receptor 3

Death receptor 3, also known as tumor necrosis factor receptor superfamily member 25, is a cell surface receptor of the tumor necrosis factor receptor superfamily which mediates apoptotic signalling and differentiation. Its only known TNFSF ligan ...

DEDD

This gene encodes a protein that contains a death effector domain DED. DED is a protein–protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce ...

Dehydrodolichyl diphosphate synthase

Dehydrodolichyl diphosphate dedol-PP synthase catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier lipid required for the biosynthesis of several classes of glycoproteins.

DENN1B

DENN1B is a human gene, located on chromosome 1. The gene is hypothesized by Danish scientists Klaus Bonnelykke and Hans Bisgaard to be related to asthma.

Deoxyribonuclease 2 beta

The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. U ...

Deoxyribonuclease II

Deoxyribonuclease II is an endonuclease that hydrolyzes phosphodiester linkages of deoxyribonucleotide in native and denatured DNA, yielding products with 3-phosphates and 5-hydroxyl ends, which occurs as a result of single-strand cleaving mechan ...

Dimethylallyltranstransferase

Dimethylallyltranstransferase, also known as farnesylpyrophosphate synthase or as farnesyldiphosphate synthase, is an enzyme that in humans is encoded by the FDPS gene and catalyzes the transformation of dimethylallylpyrophosphate and isopentenyl ...

Dimethylargininase

In the field of enzymology, a dimethylargininase, also known as a dimethylarginine dimethylaminohydrolase, is an enzyme that catalyzes the chemical reaction: N-omega,N-omega-methyl-L-arginine + H 2 O ⇌ {\displaystyle \rightleftharpoons } dimethyl ...

DIRAS3 (gene)

GTP-binding protein Di-Ras3 also known as aplysia ras homology member I is a protein that in humans is encoded by the DIRAS3 gene. This gene is a member of the RAS superfamily and is expressed in normal ovarian and breast epithelial cells, but no ...