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Fibrinogen alpha chain

The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein composed of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, which is th ...

Fibrinogen beta chain

Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation. The protein encoded by this gene is the beta component of fibrinogen, in the blood is a glycoprotein consis ...

Fibrinogen gamma chain

Fibrinogen gamma chain, also known as FGG, is a human gene found on Chromosome 4. The protein encoded by this gene is the gamma component of fibrinogen, in the blood is a glycoprotein consisting of three pairs of nonidentical polypeptide chains. ...

Fibroblast growth factor receptor-like 1

Fibroblast growth factor receptor-like 1 is a protein that in humans is encoded by the FGFRL1 gene. The protein encoded by this gene is a member of the receptor fibroblast growth factor whiskey family, where amino acid sequence is highly conserve ...

FIP1L1

Factor interacting with PAPOLA and CPSF1 is a protein that in humans is encoded by the FIP1L1 gene. An medically important aspect of the FIP1L1 gene is its fusion with other genes to form fusion genes which cause clonal hypereosinophilia and leuk ...

GAB1

The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. The encoded protein is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and ...

GAK (protein)

In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases CDKs, whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylatio ...

GBA3

Cytosolic beta-glucosidase, also known as cytosolic beta-glucosidase-like protein 1, is a beta-glucosidase enzyme that in humans is encoded by the GBA3 gene.

Glutamyl aminopeptidase

Glutamyl aminopeptidase is an enzyme encoded by the ENPEP gene. Glutamyl aminopeptidase has also recently been designated CD249. Glutamyl-amino peptidases-is a zinc-dependent membrane-bound amino peptidases, which catalyzes the cleavage of glutam ...

GRIA2

Glutamate ionotropic receptor AMPA type subunit 2 is a protein that in humans is encoded by the GRIA2 gene.

GRID2

Glutamate receptor, ionotropic, delta 2, also known as GluD2, GluRδ2, or δ 2, is a protein that in humans is encoded by the GRID2 gene. This protein together with GluD1 belongs to the delta receptor subtype of ionotropic glutamate receptors. They ...

GRK4

G protein-coupled receptor kinase 4 is an enzyme that in humans is encoded by the GRK4 gene. This gene encodes a member of the G protein-binding receptor kinase subfamily of the SER / TP protein kinase family, and many are very similar to GRK5 an ...

GRXCR1

Glutaredoxin domain-containing cysteine-rich protein 1 is a protein that in humans is encoded by the GRXCR1 gene. This gene is one of 60 loci associated with autosomal recessive non-syndromic hearing loss. This gene encodes a protein that contain ...

GUCY1A3

Soluble guanylate cyclase sGC, a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs. Mutatio ...

GUCY1B3

Soluble guanylate cyclase sGC, a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.

GYPB

Glycophorin B also known as sialoglycoprotein delta and SS-active sialoglycoprotein is a protein which in humans is encoded by the GYPB gene. GYPB has also recently been designated CD235b.

GYPE

Glycophorin-E is a protein that in humans is encoded by the GYPE gene. The protein encoded by this gene is a sialoglycoprotein and a type I membrane protein. He is a member of a gene family with GPA and GPB genes. This encoded protein can carry t ...

HERC5

Probable E3 ubiquitin-protein ligase HERC5 is an enzyme that in humans is encoded by the HERC5 gene. This gene is a member of the Herc family of ubiquitin ligase and encodes a protein with the ha domain and five RCC1 repeats. Proinflammatory cyto ...

HGFAC

Hepatocyte growth factor activator is a protein that in humans is encoded by the HGFAC gene. The protein encoded by this gene belongs to peptidase family S1. It is first synthesized as inactive single-chain precursor before being activated to a h ...

HHIP

Hedgehog interacting protein is a protein that in humans is encoded by the HHIP gene. This gene encodes a protein similar to the mouse hedgehog interacting protein, a regulatory component of the hedgehog signaling path. Members of the hedgehog fa ...

HIP2

Ubiquitin-conjugating enzyme E2 K is a protein that in humans is encoded by the UBE2K gene. The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. He selectively in the large region at the station of huntingtin. This ...

HNRPD

Heterogeneous nuclear ribonucleoprotein D0 also known as AU-rich element RNA-binding protein 1 is a protein that in humans is encoded by the HNRNPD gene. Alternative splicing of this gene results in four transcript variants.

HNRPDL

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins hnRNPs. The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA hnRNA. These proteins are associated with pre-mRNAs ...

HPGD

Hydroxyprostaglandin dehydrogenase 15-, also called 15-hydroxyprostaglandin dehydrogenase, is an enzyme that in humans is encoded by the HPGD gene. In melanocytic cells the HPGD gene expression may be regulated by MITF.

HS3ST1

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosyntheti ...

IGFBP7

Insulin-like growth factor-binding protein 7 is a protein that in humans is encoded by the IGFBP7 gene. The major function of the protein is the regulation of availability of insulin-like growth factors in tissue as well as in modulating IGF bind ...

INPP4B

Inositol polyphosphate-4-phosphatase, type II, 105kDa is a protein that in humans is encoded by the INPP4B gene. INPP4B encodes the Inositol polyphosphate 4-phosphatase type II, dual specificity phosphatase. INPP4B is involved in phosphatidylinos ...

Interleukin 15

Interleukin-15 is a cytokine with structural similarity to Interleukin-2. Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain and the common gamma chain. IL-15 is secreted by mononuclear phagocytes f ...

Interleukin 21

Interleukin 21 is a protein that in humans is encoded by the IL21 gene. Interleukin-21 is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer NK-cells and cytotoxic T cells that can destroy virus ...

INTS12

Integrator complex subunit 12 also known as PHD finger protein 22 is a protein that in humans is encoded by the INTS12 gene. INTS12 is a subunit of the integrator complex, which associates with the C-terminal domain of RNA polymerase II large sub ...

KIAA0922

Transmembrane protein 131-like, alternatively named uncharacterized protein KIAA0922, is an integral transmembrane protein encoded by the human gene KIAA0922 that is significantly conserved in eukaryotes, at least through protists. Although the f ...

KIAA1530

KIAA1530 is a protein that in humans that is encoded by the KIAA1530 gene, also known as UVSSA. Mutations in this gene have been identified to cause the UV-sensitive syndrome and recently, its important role in Transcription-coupled repair has be ...

KLKB1

Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide ...

LCORL

This gene encodes a transcription factor that appears to function in spermatogenesis. Polymorphisms in this gene are associated with measures of skeletal frame size and adult height. Alternative splicing results in multiple transcript variants.

LDL-receptor-related protein-associated protein

Low density lipoprotein receptor-related protein-associated protein 1 also known as LRPAP1 or RAP is a chaperone protein which in humans is encoded by the LRPAP1 gene.

Lecithin retinol acyltransferase

Lecithin retinol acyltransferase is a microsomal enzyme that catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester during phototransduction, an essential reaction for the retinoid cycle in visual system and vitamin A stat ...

LIAS (gene)

The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-+-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoa ...

LRBA

Lipopolysaccharide-responsive and beige-like anchor protein is a protein that in humans is encoded by the LRBA gene. Patients with the syndrome Chediak-Higashi CHS1, MIM 214500 suffer from a systemic immunodeficiency involving defects in polarize ...

LSM6

U6 snRNA-associated Sm-like protein LSm6 is a protein that in humans is encoded by the LSM6 gene. And SM-like proteins were discovered in various organisms based on sequence homology with the family of cm SNRPD2 protein, MIM 601061. Sm-like prote ...

LYAR

Cell growth-regulating nucleolar protein is a protein that in humans is encoded by the LYAR gene. The laboratory contains a zinc finger motif and three copies of nuclear localization signals. FLNR mainly localized in the nucleoli. FLNR was presen ...

MAB21L2

This gene is similar to the C. elegans MAB-21 cell fate-determining gene, a downstream target of transforming growth factor-beta signaling. It is thought that this gene may be involved in neural development. The protein encoded by this gene is pr ...

MAD2L1

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogen ...

MAN2B2

Epididymis-specific alpha-mannosidase is an enzyme that in humans is encoded by the MAN2B2 gene. The epididymis-specific alpha-mannosidase precursors Alpha mannosidase member 2B class core-specific lysosomal alpha-1.6-Mannosidase the epididymis-s ...

MAP2K1IP1

The protein encoded by this gene was identified as an interacting protein that binds specifically to MAP kinase MAP2K1/MEK1 and to MAP kinase MAPK2/ERK1. This protein enhances the activation of MAPK2, and thus is thought to function as an adaptor ...

MAPK10

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, tran ...

MFSD7

Major facilitator superfamily domain containing 7 is a protein that in humans is encoded by the MFSD7 gene. MFSD7is atypical SLC, thus, predicted Transporter of the SLC. It clusters phylogenetically on atypical MFS family Transporter 5AMTF5 and f ...

MFSD8

Major facilitator superfamily domain containing 8 also called MFSD8 is a protein that in humans is encoded by the MFSD8 gene. MFSD8 is an atypical SLC, thus a predicted SLC transporter. It clusters phylogenetically to the Atypical MFS Transporter ...

MGST2

Microsomal glutathione S-transferase 2 is an enzyme that in humans is encoded by the MGST2 gene. Membrane-associated proteins in the MAPEG family of eicosanoids and glutathione metabolism consists of six human proteins, several of which are invol ...

MIR1269A

microRNAs miRNAs are short 20-24 nt non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymer ...

MMAA

The protein encoded by this gene is involved in the translocation of cobalamin into the mitochondrion, where it is used in the final steps of adenosylcobalamin synthesis. Adenosylcobalamin is a coenzyme required for the activity of methylmalonyl- ...