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APBB1IP

Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, also known as APBB1-interacting protein 1 or Rap1-GTP-interacting adapter molecule is a protein that in humans is encoded by the APBB1IP gene.

ARID5B

AT-rich interactive domain-containing protein 5B is a protein that in humans is encoded by the ARID5B gene. Alternative names for this gene include recognition factor of the modulator 23.

ARL3

ADP-ribosylation factor-like 3 is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL3 binds guanine nucleotides but lacks ADP-ribosylation factor activity.

Artemis (protein)

Artemis is a nuclear protein that is involved in VDJ recombination and DNA repair. The protein has endonuclease activity on 5 and 3 overhangs and hairpins when complexed with PRKDC. Cells with a deficiency in Artemis are more sensitive than norma ...

ASAH2B

Neutral ceramidase B also known as non-lysosomal ceramidase B or N-acylsphingosine amidohydrolase 2B or ASAH2B is a ceramidase enzyme which in humans is encoded by the ASAH2B gene.

ASB13

Ankyrin repeat and SOCS box protein 13 is a protein that in humans is encoded by the ASB13 gene. The protein encoded by this gene is a member of the ankyrin repeat and SOC box containing family of ASB proteins. They contain ankyrin repeat sequenc ...

ATP5C1

The human ATP5F1C gene encodes the gamma subunit of an enzyme called mitochondrial ATP synthase. This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis ATP using an electrochemical gradient o ...

BAMBI

This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta TGF beta family, whose members play important roles in signal transduction in many developmental and pathological processes. The ...

BCCIP

BRCA2 and CDKN1A-interacting protein is a protein that in humans is encoded by the BCCIP gene. This gene product was isolated based on its interaction with BRCA2 and P21 proteins. It is an evolutionary conserved nuclear protein with multiple inte ...

Beta-1 adrenergic receptor

The beta-1 adrenergic receptor, also known as ADRB1, is a beta-adrenergic receptor, and also denotes the human gene encoding it. It is a G-protein coupled receptor associated with the Gs heterotrimeric G-protein and is expressed predominantly in ...

BMI1

Polycomb complex protein BMI-1 also known as polycomb group RING finger protein 4 or RING finger protein 51 is a protein that in humans is encoded by the BMI1 gene. BMI1 is a polycomb ring finger oncogene.

BTAF1

Initiation of transcription by RNA polymerase II requires the assistance of TATA box-binding protein TBP, MIM 600075 and TBP-associated factors, or TAFs e.g., TAF2B, MIM 604912, in 2 distinct complexes, TFIID and B-TFIID. The TFIID complex is com ...

BTRC (gene)

F-box/WD repeat-containing protein 1A also known as βTrCP1 or Fbxw1 or hsSlimb or pIkappaBalpha-E3 receptor subunit is a protein that in humans is encoded by the BTRC gene. This gene encodes a member of f-box family protein, which is characterize ...

C10orf67

Chromosome 10 open reading frame 67, also known as C10orf115, LINC01552, and BA215C7.4, is an un-characterized human protein-coding gene. Several studies indicate a possible link between genetic polymorphisms of this and several other genes to ch ...

C10orf71

C10orf71 is a gene located on chromosome 10 open reading frame 71. It is primarily understood that this gene is moderately expressed in muscle tissue and cardiac tissue.

C10orf76

C10orf76 or chromosome 10 open reading frame 76, also known as UPF0668, is a protein that in humans is encoded by the c10orf76 gene. Its function is not currently known, but experimental evidence has suggested that it may be involved in transcrip ...

CAMK1D

This gene encodes a member of the Ca2+/calmodulin-dependent protein kinase 1 subfamily of serine/threonine kinases. The encoded protein may be involved in the regulation of granulocyte function through the chemokine signal transduction pathway. A ...

CAMK2G

The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca2+/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian ...

CCDC186

CCDC186 is a protein that in humans is encoded by the CCDC186 gene The CCDC186 gene is also known as the CTCL-tumor associated antigen with accession number NM_018017.

CEP55

Centrosomal protein of 55 kDa is a protein that in humans is encoded by the CEP55 gene. CEP55 is a mitotic phosphoprotein, which plays a key role in cytokinesis, the last stage of cell division.

Choline acetyltransferase

Choline acetyltransferase is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine. ChAT catalyzes the transfer of an acetyl group from the coenzyme acetyl-CoA to choline, yielding acetylcholine. ChAT is found i ...

CHUK

Inhibitor of nuclear factor kappa-B kinase subunit alpha also known as IKK1 or conserved helix-loop-helix ubiquitous kinase is a protein kinase that in humans is encoded by the CHUK gene. IKK-α is part of the IκB kinase complex that plays an impo ...

Collagen, type XIII, alpha 1

Collagen alpha-1 chain is a protein that in humans is encoded by the COL13A1 gene. This gene encodes the alpha chain of one of the nonfibrillar collagens. The function of this gene product is not known, however, it was discovered in small quantit ...

Collagen, type XVII, alpha 1

Collagen XVII, previously called BP180, is a transmembrane protein which plays a critical role in maintaining the linkage between the intracellular and the extracellular structural elements involved in epidermal adhesion, identified by Diaz and c ...

COX15

Cytochrome c oxidase assembly protein COX15 homolog, also known as heme A synthase, is a protein that in humans is encoded by the COX15 gene. This protein localizes to the inner mitochondrial membrane and involved in heme A biosynthesis. COX15 is ...

CPN1

Carboxypeptidase N catalytic chain is an enzyme that in humans is encoded by the CPN1 gene. Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in th ...

Cubilin

Cubilin CUBN acts as a receptor for intrinsic factor-vitamin B 12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubilin shows a restricted mode of expression according to protein profiling and transcriptomics ana ...

CUGBP2

CUGBP, Elav-like family member 2, also known as Etr-3 is a protein that in humans is encoded by the CELF2 gene. Members of the CELF / BRUNOL protein family of RNA-binding proteins and contains two N-terminal RNA recognition motif RRM domains, one ...

CYP2C18

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This prot ...

CYP26A1

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endo ...

CYP26C1

CYP26C1 is a protein which in humans is encoded by the CYP26C1 gene. This gene encodes a member of cytochrome P450 superfamily of enzymes. Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and s ...

DCLRE1A

DNA cross-link repair 1A protein is a protein that in humans is encoded by the DCLRE1A gene. These DNA cross-links prevent strand separation, thus physically blocking transcription, replication and segregation of DNA. DCLRE1A is one of several ev ...

DDIT4

DNA-damage-inducible transcript 4 protein also known as protein regulated in development and DNA damage response 1 is a protein that in humans is encoded by the DDIT4 gene.

DDX21

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp DEAD, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclea ...

DDX50

ATP-dependent RNA helicase DDX50 is an enzyme that in humans is encoded by the DDX50 gene. Dead box proteins, characterized by conservative motif ASP-STU-Ala-ASP, dead putative RNA helicase. They are involved in a number of cellular processes, in ...

DHTKD1

Dehydrogenase E1 and transketolase domain containing 1 is a protein that in humans is encoded by the DHTKD1 gene. This gene encodes a component of a mitochondrial 2-oxoglutarate-dehydrogenase-complex-like protein involved in the degradation pathw ...

DHX32

Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 is an enzyme that in humans is encoded by the DHX32 gene. Dead box proteins, characterized by conservative motif ASP-STU-Ala-ASP, dead putative RNA helicase. They are involved in ...

Disco interacting protein 2 homolog c

This gene encodes a member of the disco-interacting protein homolog 2 family. The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system.

DKK1

This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the Wnt signaling pathway. Dickkopf WNT signaling path ...

DLG5

This gene encodes a member of the family of discs large DLG homologs, a subset of the membrane-associated guanylate kinase MAGUK superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ ...

DNA2L

DNA2-like helicase is an enzyme that in humans is encoded by the DNA2 gene. Dna2, a homolog of DNA2KL present in budding yeast, possesses both helicase and nuclease activity, with which it helps catalyze early steps in homologous recombination.

Dock180

Dock180, also known as DOCK1, is a large protein involved in intracellular signalling networks. It is the mammalian ortholog of the C. elegans protein CED-5 and belongs to the DOCK family of Guanine nucleotide exchange factors.

DRD1IP

The protein encoded by this gene is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with ...

DUSP5

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negati ...

DUSP13

Members of the protein tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family ...

Ectonucleoside triphosphate diphosphohydrolase 7

This gene encodes a purine-converting ectoenzyme which belongs to the ecto-nucleoside triphosphate diphosphohydrolase E-NTPDase family. The encoded protein hydrolyzes extracellular nucleoside triphosphates to nucleoside monophosphates as part of ...

EIF3A

Eukaryotic translation initiation factor 3 subunit A is a protein that in humans is encoded by the EIF3A gene. It is one of the subunits of Eukaryotic initiation factor 3 a multiprotein complex playing major roles in translation initiation in euk ...

EIF4EBP2

EIF4EBP2 knockout mice have been used as an animal model of autism. Mice without the Eif4ebp2 gene exhibited autism-like symptoms, including poor social interaction, altered communication and repetitive behaviors. Knockout mice have high levels o ...

Enkurin

Enkurin is a protein that in humans is encoded by the ENKUR gene. Enkurin interacts with transient receptor potential canonical cation channels checkboxes for example, TRPC1, and functions as an adapter protein, tethering signal transduction prot ...

ERCC6

DNA excision repair protein ERCC-6 is a protein that in humans is encoded by the ERCC6 gene. The ERCC6 gene is located on the long arm of chromosome 10 at position 11.23. Having 1 or more copies of a mutated ERCC6 causes Cockayne syndrome, type II.