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Sympathomimetic drug

Sympathomimetic drugs are stimulant compounds which mimic the effects of endogenous agonists of the sympathetic nervous system. The primary endogenous agonists of the sympathetic nervous system are the catecholamines, which function as both neuro ...

Cyclopentamine

Cyclopentamine is a sympathomimetic alkylamine, classified as a vasoconstrictor. Cyclopentamine was indicated in the past as an over-the-counter medication for use as a nasal decongestant, notably in Europe and Australia, but has now been largely ...

1.3-Dimethylbutylamine

1.3-Dimethylbutylamine, is a stimulant drug structurally related to methylhexanamine where a butyl group replaces the pentyl group. The compound is an aliphatic amine. The hydrochloride and the citrate salt of DMBA was identified as unapproved in ...

Corex

Corex is a cough syrup sold by Pfizer Inc. It is available in India, Pakistan, Bangladesh and a few other South Asian countries. Corex is a prescribed medicine. Its active ingredients are chlorpheniramine maleate and codeine phosphate.

Dimemorfan

Dimemorfan, or dimemorfan phosphate, also known as 3.17-dimethylmorphinan, is an antitussive of the morphinan family that is widely used in Japan and is also marketed in Spain and Italy. It was developed by Yamanouchi Pharmaceutical and introduce ...

Pholcodine

Pholcodine is a drug which is an opioid cough suppressant. It helps suppress unproductive coughs and also has a mild sedative effect, but has little or no analgesic effects. It is also known as morpholinylethylmorphine and homocodeine. Folcodin f ...

Decongestant

A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract. The active ingredient in most decongestants is either pseudoephedrine or phenylephrine. Intranasal co ...

Calcium hexamine thiocyanate

Calcium hexamine thiocyanate is a pharmaceutical drug that has been used in nasal preparations. It contains hexamine and thiocyanate. This combination has also been used for the treatment of urinary tract infections.

ChestEze

ChestEze is a British over-the-counter pharmaceutical product manufactured by Novartis for "relief of bronchial cough, wheezing, breathlessness and other symptoms of asthmatic bronchitis and to clear the chest of mucus following upper respiratory ...

Cold capsule

Both products contained chlorpheniramine maleate an antihistamine and phenylpropanolamine hydrochloride a decongestant but differed in their doses. Both products contained 75 mg of phenylpropanolamine hydrochloride, but Cold Capsule IV contained ...

Sobrerol

Sobrerol was discovered by Ascanio Sobrero as an oxidation product of terpenes. Later the oxidation and reduction reactions of chiral pinene lead also to several possible isomers of carvone the corresponding cyclohexyl ketone dehydrated at the is ...

Terpin

Terpin, used as the hydrate, is an expectorant, used to loosen mucus in patients presenting with acute or chronic bronchitis, and related conditions. It is derived from sources such as oil of turpentine, oregano, thyme and eucalyptus. It was popu ...

Respiratory Pharmacology

There are several categories of respiratory drugs, each specific to a drugs purpose and mode of action. The following is a list of key pharmaceuticals in the prevention and treatment of respiratory-related ailments.

Chlorcyclizine

Chlorcyclizine is a first-generation antihistamine of the diphenylmethylpiperazine group marketed in the United States and certain other countries. It is used primarily to treat allergy symptoms such as rhinitis, urticaria, and pruritus, and may ...

Etymemazine

Etymemazine is an antipsychotic, antihistamine and anticholinergic drug of the phenothiazine chemical class, structurally related to cyamemazine and methotrimeprazine.

Mast cell stabilizer

Mast cell stabilizers are chromone medications used to prevent or control certain allergic disorders. They block mast cell degranulation, stabilizing the cell and thereby preventing the release of histamine and related mediators. One suspected ph ...

Moxastine

Moxastine is an antihistamine and anticholinergic. It was developed in Czechoslovakia and is sold in the form of the hydrochloride as an antihistamine Alfadryl. This, with 8-chlorotheophylline, a component of the cocrystal / salt teoclate moxasti ...

Pirbuterol

Pirbuterol is a short-acting β 2 adrenoreceptor agonist with bronchodilating action used in the treatment of asthma, available as a breath-activated metered-dose inhaler. It was patented in 1971 and came into medical use in 1983.

Suplatast tosilate

Suplatast tosilate is a Th2 cytokine inhibitor which is used as an antiallergic drug. It has been suggested and applied in the treatment of Kimuras disease a few times.

Tezacaftor

Tezacaftor, development code VX-661, is a drug that is sold as a fixed-dose combination with ivacaftor as Symdeko. It is used for the treatment of cystic fibrosis in people six years and older, who have specific gene mutations. In 2018, the U.S. ...

Topical decongestant

Topical decongestants are decongestants applied directly to the nasal cavity. Their effectiveness by themselves in the common cold appears to have a small benefit in adults. Topical decongestants should only be used in patients for a maximum of 5 ...

Tramazoline

Tramazoline is a chemical that is used in the form of tramazoline hydrochloride in nasal decongestant preparations. It is an α-adrenergic receptor agonist that inhibits secretion of nasal mucus. It was patented in 1961 and came into medical use i ...

Antithyroid agent

An antithyroid agent is a hormone antagonist acting upon thyroid hormones. The main antithyroid drugs are carbimazole in UK, methimazole in the USA, and propylthiouracil / PTU. Less common antithyroid agent is potassium perchlorate.

Strontium ranelate

Strontium ranelate, a strontium salt of ranelic acid, is a medication for osteoporosis marketed as Protelos or Protos by Servier. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both incr ...

Emicerfont

Emicerfont is a drug developed by GlaxoSmithKline which acts as a CRF-1 antagonist. Corticotropin releasing factor, also known as Corticotropin releasing hormone, is an endogenous peptide hormone which is released in response to various triggers ...

Prednylidene

Prednylidene is a glucocorticoid for systemic use. Substitution at position 16 leads to more potent corticosteroids. The additional steric Bulk provided such substituents adjacent to the side chain dihydroxyacetone Guide also protects against the ...

Vasopressin analogue

Vasopressin analogues are chemicals similar in function but not necessarily similar in structure to vasopressin, such as desmopressin. Desmopressin is used as an oral spray to treat diseases where ADH is not produced in sufficient quantity, or va ...

Diarylquinoline

Diarylquinolines are a chemical class of drugs that treat tuberculosis. They target subunit c of mycobacterial ATP synthase, inhibiting the enzyme so mycobacterium tuberculosis cannot synthesise ATP. This effectively kills the bacteria. Although ...

Ethambutol/isoniazid

Ethambutol/isoniazid is a medication used to treat tuberculosis. It is a fixed dose combination of ethambutol and isoniazid. It is used along with other antituberculosis medication. It is taken by mouth. Side effects of these basic drugs. More co ...

Nucleic acid inhibitor

A nucleic acid inhibitor is a type of antibacterial that acts by inhibiting the production of nucleic acids. There are two major classes: DNA inhibitors and RNA inhibitors. The antifungal flucytosine acts in a similar manner.

Thiopeptide

Thiopeptides are a class of peptide antibiotics produced by bacteria. They have antibiotic activity against Gram-positive bacteria, but little or no activity against Gram-negative bacteria. Many of the members of this class show activity against ...

Nosiheptide

Nosiheptide is classified, along with several others, as an e series thiopeptide characterized by a nitrogen containing, 6-membered heterocycle in a 2.3.5.6 substituted fashion central to multiple azoles or azolines and dehydroamino acids along w ...

Aminopenicillin

The aminopenicillins are a group of antibiotics in the penicillin family that are structural analogs of ampicillin. Like other penicillins and beta-lactam antibiotics, they contain a beta-lactam ring that is crucial to its antibacterial activity. ...

Amphenicol

Amphenicols are a class of antibiotics with a phenylpropanoid structure. They function by blocking the enzyme peptidyl transferase on the 50S ribosome subunit of bacteria. Examples of amphenicols include chloramphenicol, thiamphenicol, azidamfeni ...

Antistaphylococcal penicillins

Penicillin resistance in Staphylococcus aureus appeared very soon after penicillin entered general clinical use in 1943, and the mechanism of resistance was the production of β-lactamase. Modification of the penicillin molecule so that it was res ...

Azalide

Azalides are a class of macrolide antibiotics which contain a nitrogen in the macrolide ring. This imparts different pharmacokinetic properties and is associated with greater stability of the molecule. One such azalide is the antibiotic azithromycin.

Betamipron

Betamipron or N -benzoyl-β-alanine is a chemical compound which is used together with panipenem to inhibit panipenem uptake into the renal tubule and prevent nephrotoxicity.

Carbacephem

Carbacephems are a class of synthetic antibiotics, based on the structure of cephalosporin, a cephem. Carbacephems are similar to cephems, but with a carbon substituted for the sulfur. It prevents bacterial cell division by inhibiting cell wall s ...

Carboxypenicillin

The carboxypenicillins feature the beta-lactam backbone of all penicillins but also feature a carboxylic acid or carboxylic acid ester group in the variable side-chain.

Cephamycin

Cephamycins are a group of β-lactam antibiotics. They are very similar to cephalosporins, and the cephamycins are sometimes classified as cephalosporins. Like cephalosporins, cephamycins are based on the cephem nucleus. Unlike most cephalosporins ...

JNJ-Q2

JNJ-Q2 is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and skin-structure infections and community-acquired pneumonia. Specifically, JNJ-Q2 is being actively studied for treatment o ...

Monobactam

Monobactams are monocyclic and bacterially-produced β-lactam antibiotics. The β-lactam ring is not fused to another ring, in contrast to most other β-lactams. Monobactams are effective only against aerobic Gram-negative bacteria. Siderophore-conj ...

Nocardicin A

Nocardicin A is a monocyclic β-lactam antibiotic included in the monobactam subclass. It is obtained from the fermentation broth of a strain of actinomycetes Nocardia uniformis subsp. tsuyamenensis as a metabolic product catalyzed by the enzyme n ...

Pipemidic acid

Pipemidic acid is a member of the pyridopyrimidine class of antibacterials, which display some overlap in mechanism of action with analogous pyridone-containing quinolones. It was introduced in 1979 and is active against gram negative and some gr ...

Pristinamycin IIA

Pristinamycin IIA is a macrolide antibiotic. It is a member of the streptogramin A group of antibiotics and one component of pristinamycin.

Radezolid

Radezolid is a novel oxazolidinone antibiotic being developed by Melinta Therapeutics, Inc. for the treatment of bacterial acne.

Sulfachlorpyridazine

Sulfachlorpyridazine is a sulfonamide antibiotic drug used in poultry farming. It has been marketed as Vetisulid for use in cattle, swine and birds.

Sulfadimidine

Sulfadimidine or sulfamethazine is a sulfonamide antibacterial. There are non-standardized abbreviations for it as "sulfadimidine" abbreviated SDI and more common, but less reliably SDD B and as "sulfamethazine" abbreviated SMT and more often, bu ...

Sulfamethoxypyridazine

Sulfamethoxypyridazine is a sulfonamide antibacterial. It is prescribed for vaginal irritation and acute of thrush. It is also used in the treatment of dermatitis herpetiformis, where it is an alternative therapy with Dapsone. Sulfamethoxypyridaz ...

Sulfisomidine

Sulfisomidine, also known as sulphasomidine, sulfamethin and sulfaisodimidine, is a sulfonamide antibacterial. It is closely related to sulfadimidine.